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    E3 ubiquitin-protein ligase RNF170-like protein (DUF 1232) [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838857, updated on 18-Sep-2024

    Summary

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    Official Full Name
    E3 ubiquitin-protein ligase RNF170-like protein (DUF 1232)
    Primary source
    TAIR:AT1G22510
    Locus tag
    AT1G22510
    See related
    Araport:AT1G22510
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F12K8.14; F12K8_14
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    5
    Sequence:
    Chromosome: 1; NC_003070.9 (7950818..7952832, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene basic helix-loop-helix (bHLH) DNA-binding superfamily protein Neighboring gene ncRNA Neighboring gene RING/U-box superfamily protein Neighboring gene ncRNA Neighboring gene MICOS complex subunit Mic10-like protein (DUF543) Neighboring gene PATELLIN 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A proteomics dissection of Arabidopsis thaliana vacuoles isolated from cell culture. Jaquinod M, et al. Mol Cell Proteomics, 2007 Mar. PMID 17151019, Free PMC Article
    2. A high content in lipid-modified peripheral proteins and integral receptor kinases features in the arabidopsis plasma membrane proteome. Marmagne A, et al. Mol Cell Proteomics, 2007 Nov. PMID 17644812
    3. Putative glycosyltransferases and other plant Golgi apparatus proteins are revealed by LOPIT proteomics. Nikolovski N, et al. Plant Physiol, 2012 Oct. PMID 22923678, Free PMC Article
    4. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article
    5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_001198135.1
    NM_102100.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in endoplasmic reticulum HDA PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus HDA PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plant-type vacuole HDA PubMed 
    located_in plasma membrane HDA PubMed 

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase RNF170-like protein (DUF 1232)
    NP_001185064.1
    • RING/U-box protein with domain of unknown function (DUF 1232); FUNCTIONS IN: zinc ion binding; EXPRESSED IN: 19 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF1232 (InterPro:IPR010652); BEST Arabidopsis thaliana protein match is: RING/U-box protein with domain of unknown function (DUF 1232) (TAIR:AT1G72175.1).
    NP_564172.1
    • FUNCTIONS IN: zinc ion binding; LOCATED IN: plasma membrane; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF1232 (InterPro:IPR010652), Zinc finger, RING-type, conserved site (InterPro:IPR017907), Zinc finger, RING-type (InterPro:IPR001841); BEST Arabidopsis thaliana protein match is: RING/U-box protein with domain of unknown function (DUF 1232) (TAIR:AT1G72175.1); Has 639 Blast hits to 639 proteins in 126 species: Archae - 0; Bacteria - 17; Metazoa - 440; Fungi - 43; Plants - 76; Viruses - 2; Other Eukaryotes - 61 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      7950818..7952832 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001198135.1 → NP_001185064.1  E3 ubiquitin-protein ligase RNF170-like protein (DUF 1232) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001185064.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9VJ88, A0A654EDP7, F4I1E4
      Conserved Domains (1) summary
      cl17238
      Location:49 → 71
      RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

    2. NM_102100.3 → NP_564172.1  E3 ubiquitin-protein ligase RNF170-like protein (DUF 1232) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_564172.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178W3X0, Q0WWX8, Q8LDL6
      Conserved Domains (1) summary
      cd00162
      Location:10 → 56
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
    Nucleotide Protein
    Heading Accession and Version

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