U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    NRS/ER nucleotide-rhamnose synthase/epimerase-reductase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 842603, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    NRS/ER
    Official Full Name
    nucleotide-rhamnose synthase/epimerase-reductase
    Primary source
    TAIR:AT1G63000
    Locus tag
    AT1G63000
    See related
    Araport:AT1G63000
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ''UDP-4-KETO-6-DEOXY-D-GLUCOSE-3; 5-EPIMERASE-4-REDUCTASE 1; 5-EPIMERASE-4-REDUCTASE 1''; F16P17.17; F16P17_17; nucleotide-rhamnose synthase/epimerase-reductase; UDP-4-KETO-6-DEOXY-D-GLUCOSE-3; UER1
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See NRS/ER in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    2
    Sequence:
    Chromosome: 1; NC_003070.9 (23342211..23344120)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene transmembrane protein, putative (DUF1191) Neighboring gene homeobox knotted-like protein Neighboring gene ncRNA Neighboring gene Major Facilitator Superfamily with SPX (SYG1/Pho81/XPR1) domain-containing protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Structural and biochemical insights into nucleotide-rhamnose synthase/epimerase-reductase from Arabidopsis thaliana. Han X, et al. Biochim Biophys Acta, 2015 Oct. PMID 26116145
    2. A bifunctional 3,5-epimerase/4-keto reductase for nucleotide-rhamnose synthesis in Arabidopsis. Watt G, et al. Plant Physiol, 2004 Apr. PMID 15020741, Free PMC Article
    3. Functional analysis of Arabidopsis thaliana RHM2/MUM4, a multidomain protein involved in UDP-D-glucose to UDP-L-rhamnose conversion. Oka T, et al. J Biol Chem, 2007 Feb 23. PMID 17190829
    4. Protein and metabolite composition of Arabidopsis stress granules. Kosmacz M, et al. New Phytol, 2019 May. PMID 30664249
    5. A high content in lipid-modified peripheral proteins and integral receptor kinases features in the arabidopsis plasma membrane proteome. Marmagne A, et al. Mol Cell Proteomics, 2007 Nov. PMID 17644812

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. NRS/ER functions as a metal ion independent homodimer that forms through hydrophobic interactions via a four-helix bundle.
      Title: Structural and biochemical insights into nucleotide-rhamnose synthase/epimerase-reductase from Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    Pathways from PubChem

    Go to the top of the page

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    NM_104978.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables UDP-4-keto-6-deoxy-glucose-3,5-epimerase activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables UDP-4-keto-rhamnose-4-keto-reductase activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables dTDP-4-dehydrorhamnose 3,5-epimerase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables dTDP-4-dehydrorhamnose reductase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within UDP-rhamnose biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within dTDP-rhamnose biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in dTDP-rhamnose biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytoplasmic stress granule IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane HDA PubMed 
    located_in plasmodesma HDA PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    nucleotide-rhamnose synthase/epimerase-reductase
    NP_564806.1
    • nucleotide-rhamnose synthase/epimerase-reductase (NRS/ER); FUNCTIONS IN: UDP-4-keto-rhamnose-4-keto-reductase activity, dTDP-4-dehydrorhamnose reductase activity, UDP-4-keto-6-deoxy-glucose-3,5-epimerase activity, dTDP-4-dehydrorhamnose 3,5-epimerase activity; INVOLVED IN: dTDP-rhamnose biosynthetic process, UDP-rhamnose biosynthetic process; LOCATED IN: soluble fraction, plasma membrane; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: NAD(P)-binding domain (InterPro:IPR016040), dTDP-4-dehydrorhamnose reductase (InterPro:IPR005913); BEST Arabidopsis thaliana protein match is: rhamnose biosynthesis 1 (TAIR:AT1G78570.1); Has 1363 Blast hits to 1363 proteins in 432 species: Archae - 58; Bacteria - 688; Metazoa - 9; Fungi - 22; Plants - 263; Viruses - 5; Other Eukaryotes - 318 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      23342211..23344120
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_104978.5 → NP_564806.1  nucleotide-rhamnose synthase/epimerase-reductase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_564806.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8L9Z8, Q94EZ7, Q9LQ04
      UniProtKB/TrEMBL
      A0A178WGI3, A0A5S9WRY9
      Conserved Domains (1) summary
      PLN02260
      Location:13 → 300
      PLN02260; probable rhamnose biosynthetic enzyme
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LQ04.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools