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    KCS7 3-ketoacyl-CoA synthase 7 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 843456, updated on 18-Sep-2024

    Summary

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    Official Symbol
    KCS7
    Official Full Name
    3-ketoacyl-CoA synthase 7
    Primary source
    TAIR:AT1G71160
    Locus tag
    AT1G71160
    See related
    Araport:AT1G71160
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    3-ketoacyl-CoA synthase 7; F23N20.15; F23N20_15
    Summary
    Encodes KCS7, a member of the 3-ketoacyl-CoA synthase family involved in the biosynthesis of VLCFA (very long chain fatty acids).
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    Genomic context

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    See KCS7 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    1
    Sequence:
    Chromosome: 1; NC_003070.9 (26828701..26830208, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene MATE efflux family protein Neighboring gene cyclin-D1-binding protein Neighboring gene 6-phosphogluconate dehydrogenase family protein Neighboring gene 6-phosphogluconate dehydrogenase family protein Neighboring gene senescence associated gene 18

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. CUT1, an Arabidopsis gene required for cuticular wax biosynthesis and pollen fertility, encodes a very-long-chain fatty acid condensing enzyme. Millar AA, et al. Plant Cell, 1999 May. PMID 10330468, Free PMC Article
    2. Tackling functional redundancy of Arabidopsis fatty acid elongase complexes. Batsale M, et al. Front Plant Sci, 2023. PMID 36798704, Free PMC Article
    3. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables fatty acid elongase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within cutin-based cuticle development IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in fatty acid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within very long-chain fatty acid metabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    3-ketoacyl-CoA synthase 7
    NP_177272.1
    • 3-ketoacyl-CoA synthase 7 (KCS7); FUNCTIONS IN: transferase activity, transferring acyl groups other than amino-acyl groups, catalytic activity, acyltransferase activity; INVOLVED IN: very long-chain fatty acid metabolic process, cuticle development; LOCATED IN: endomembrane system, membrane; EXPRESSED IN: 6 plant structures; EXPRESSED DURING: 4 anthesis, petal differentiation and expansion stage, E expanded cotyledon stage; CONTAINS InterPro DOMAIN/s: Thiolase-like (InterPro:IPR016039), Very-long-chain 3-ketoacyl-CoA synthase (InterPro:IPR012392), 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C-terminal (InterPro:IPR013747), FAE1/Type III polyketide synthase-like protein (InterPro:IPR013601), Thiolase-like, subgroup (InterPro:IPR016038); BEST Arabidopsis thaliana protein match is: 3-ketoacyl-CoA synthase 5 (TAIR:AT1G25450.1); Has 4929 Blast hits to 4911 proteins in 1102 species: Archae - 1; Bacteria - 1504; Metazoa - 0; Fungi - 34; Plants - 3243; Viruses - 0; Other Eukaryotes - 147 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      26828701..26830208 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_105785.2 → NP_177272.1  3-ketoacyl-CoA synthase 7 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_177272.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9C992
      UniProtKB/TrEMBL
      A0A178W4M1, A0A654EMZ9
      Conserved Domains (2) summary
      pfam08392
      Location:38 → 328
      FAE1_CUT1_RppA; FAE1/Type III polyketide synthase-like protein
      cl21486
      Location:348 → 416
      Ketoacyl-synt_C; Beta-ketoacyl synthase, C-terminal domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9C992.1

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