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    WRKY22 WRKY family transcription factor [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 827896, updated on 11-Oct-2024

    Summary

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    Official Symbol
    WRKY22
    Official Full Name
    WRKY family transcription factor
    Primary source
    TAIR:AT4G01250
    Locus tag
    AT4G01250
    See related
    Araport:AT4G01250
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtWRKY22; F2N1.6; F2N1_6
    Summary
    AtWRKY22 is a member of WRKY Transcription Factor; Group II-e. It is involved in regulation of dark induced leaf senescence.
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    Genomic context

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    See WRKY22 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    3
    Sequence:
    Chromosome: 4; NC_003075.7 (522530..524249, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene Reticulon family protein Neighboring gene S-adenosyl-L-methionine-dependent methyltransferases superfamily protein Neighboring gene uncharacterized protein Neighboring gene DNA-binding storekeeper protein-related transcriptional regulator

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The transcription factor WRKY22 is required during cryo-stress acclimation in Arabidopsis shoot tips. Stock J, et al. J Exp Bot, 2020 Aug 6. PMID 32710609, Free PMC Article
    2. AtWRKY22 promotes susceptibility to aphids and modulates salicylic acid and jasmonic acid signalling. Kloth KJ, et al. J Exp Bot, 2016 May. PMID 27107291, Free PMC Article
    3. WRKY22 transcription factor mediates dark-induced leaf senescence in Arabidopsis. Zhou X, et al. Mol Cells, 2011 Apr. PMID 21359674, Free PMC Article
    4. The transcription factor WRKY22 modulates ethylene biosynthesis and root development through transactivating the transcription of ACS5 and ACO5 in Arabidopsis. Wang Z, et al. Physiol Plant, 2024 May-Jun. PMID 38837414
    5. Submergence confers immunity mediated by the WRKY22 transcription factor in Arabidopsis. Hsu FC, et al. Plant Cell, 2013 Jul. PMID 23897923, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The transcription factor WRKY22 modulates ethylene biosynthesis and root development through transactivating the transcription of ACS5 and ACO5 in Arabidopsis.
      Title: The transcription factor WRKY22 modulates ethylene biosynthesis and root development through transactivating the transcription of ACS5 and ACO5 in Arabidopsis.
    2. The transcription factor WRKY22 is required during cryo-stress acclimation in Arabidopsis shoot tips.
      Title: The transcription factor WRKY22 is required during cryo-stress acclimation in Arabidopsis shoot tips.
    3. WRKY22 modulates the interplay between the salicylic acid (SA) and jasmonic acid (JA) pathways in response to a wide range of biotic and abiotic stimuli. Its induction by aphids and its role in suppressing SA and JA signalling make WRKY22 a potential target for aphids to manipulate host plant defences.
      Title: AtWRKY22 promotes susceptibility to aphids and modulates salicylic acid and jasmonic acid signalling.
    4. Data indicate that WRKY22 T-DNA insertion mutants wrky22-1 and wrky22-2 had lower disease resistance and lower induction of innate immunity markers, such as FLG22-INDUCED RECEPTOR-LIKE KINASE1 (FRK1) and WRKY53, after submergence.
      Title: Submergence confers immunity mediated by the WRKY22 transcription factor in Arabidopsis.
    5. AtWRKY22 participates in the dark-induced senescence signal transduction pathway
      Title: WRKY22 transcription factor mediates dark-induced leaf senescence in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_116355.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables transcription cis-regulatory region binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular response to hypoxia HEP PubMed 
    acts_upstream_of_or_within leaf senescence IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    WRKY family transcription factor
    NP_192034.1
    • WRKY22; CONTAINS InterPro DOMAIN/s: DNA-binding WRKY (InterPro:IPR003657); BEST Arabidopsis thaliana protein match is: WRKY family transcription factor (TAIR:AT4G23550.1); Has 3274 Blast hits to 2836 proteins in 187 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 3; Plants - 3256; Viruses - 0; Other Eukaryotes - 15 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      522530..524249 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_116355.3 → NP_192034.1  WRKY family transcription factor [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_192034.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O04609
      UniProtKB/TrEMBL
      A0A178V251, A0A5S9XNV0, A0A7G2EXL8
      Conserved Domains (1) summary
      pfam03106
      Location:129 → 185
      WRKY; WRKY DNA -binding domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O04609.1

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