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    ACS7 1-amino-cyclopropane-1-carboxylate synthase 7 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 828726, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ACS7
    Official Full Name
    1-amino-cyclopropane-1-carboxylate synthase 7
    Primary source
    TAIR:AT4G26200
    Locus tag
    AT4G26200
    See related
    Araport:AT4G26200
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    1-amino-cyclopropane-1-carboxylate synthase 7; ACCS7; ATACS7; T25K17.10; T25K17_10
    Summary
    Member of a family of proteins in Arabidopsis that encode 1-Amino-cyclopropane-1-carboxylate synthase, an enzyme involved in ethylene biosynthesis. Not expressed in response to IAA.
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    Genomic context

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    See ACS7 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    3
    Sequence:
    Chromosome: 4; NC_003075.7 (13275200..13277188)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene Mitochondrial substrate carrier family protein Neighboring gene Haloacid dehalogenase-like hydrolase (HAD) superfamily protein Neighboring gene Mitochondrial ATP synthase subunit G protein Neighboring gene S-adenosyl-L-methionine-dependent methyltransferases superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of Key Ubiquitination Sites Involved in the Proteasomal Degradation of AtACS7 in Arabidopsis. Tang X, et al. Int J Mol Sci, 2024 Mar 2. PMID 38474174, Free PMC Article
    2. Activation of ACS7 in Arabidopsis affects vascular development and demonstrates a link between ethylene synthesis and cambial activity. Yang S, et al. J Exp Bot, 2020 Dec 31. PMID 32926140
    3. The non-catalytic N-terminal domain of ACS7 is involved in the post-translational regulation of this gene in Arabidopsis. Xiong L, et al. J Exp Bot, 2014 Aug. PMID 24860187
    4. Loss of ACS7 confers abiotic stress tolerance by modulating ABA sensitivity and accumulation in Arabidopsis. Dong H, et al. J Exp Bot, 2011 Oct. PMID 21765163, Free PMC Article
    5. Protein Phosphatases Type 2C Group A Interact with and Regulate the Stability of ACC Synthase 7 in Arabidopsis. Marczak M, et al. Cells, 2020 Apr 15. PMID 32326656, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Identification of Key Ubiquitination Sites Involved in the Proteasomal Degradation of AtACS7 in Arabidopsis.
      Title: Identification of Key Ubiquitination Sites Involved in the Proteasomal Degradation of AtACS7 in Arabidopsis.
    2. Activation of ACS7 in Arabidopsis affects vascular development and demonstrates a link between ethylene synthesis and cambial activity.
      Title: Activation of ACS7 in Arabidopsis affects vascular development and demonstrates a link between ethylene synthesis and cambial activity.
    3. Protein Phosphatases Type 2C Group A Interact with and Regulate the Stability of ACC Synthase 7 in Arabidopsis.
      Title: Protein Phosphatases Type 2C Group A Interact with and Regulate the Stability of ACC Synthase 7 in Arabidopsis.
    4. non-catalytic N-terminus involved in its own post-translational regulation
      Title: The non-catalytic N-terminal domain of ACS7 is involved in the post-translational regulation of this gene in Arabidopsis.
    5. AtACS7 is involved in root gravitropism in a calcium-dependent manner in Arabidopsis.
      Title: A type III ACC synthase, ACS7, is involved in root gravitropism in Arabidopsis thaliana.
    6. ACS7 is turned over in a 26S proteasome-dependent manner and that degradation of ACS7 requires the E3 ligase XBAT32.
      Title: The Arabidopsis RING-type E3 ligase XBAT32 mediates the proteasomal degradation of the ethylene biosynthetic enzyme, 1-aminocyclopropane-1-carboxylate synthase 7.
    7. ACS7 acts as a negative regulator of abscisic acid accumulation under stress and appears as a node in the cross-talk between ethylene and abscisic acid.
      Title: Loss of ACS7 confers abiotic stress tolerance by modulating ABA sensitivity and accumulation in Arabidopsis.
    8. Data showed that the expression of ACS7 is induced during hypoxia.
      Title: Differential expression of genes encoding 1-aminocyclopropane-1-carboxylate synthase in Arabidopsis during hypoxia.
    9. Expression in response to plant growth regulators and abiotic stress in roots and aerial parts as demonstrated by expression of the GUS reporter in A. thaliana. [ACS7]
      Title: The GUS reporter-aided analysis of the promoter activities of Arabidopsis ACC synthase genes AtACS4, AtACS5, and AtACS7 induced by hormones and stresses.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_118753.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables 1-aminocyclopropane-1-carboxylate synthase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables pyridoxal phosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in ethylene biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within ethylene biosynthetic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    1-amino-cyclopropane-1-carboxylate synthase 7
    NP_194350.1
    • 1-amino-cyclopropane-1-carboxylate synthase 7 (ACS7); CONTAINS InterPro DOMAIN/s: 1-aminocyclopropane-1-carboxylate synthase (InterPro:IPR001176), Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Aminotransferase, class I/classII (InterPro:IPR004839), Aminotransferases, class-I, pyridoxal-phosphate-binding site (InterPro:IPR004838), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421), Pyridoxal phosphate-dependent transferase, major region, subdomain 2 (InterPro:IPR015422); BEST Arabidopsis thaliana protein match is: 1-amino-cyclopropane-1-carboxylate synthase 8 (TAIR:AT4G37770.1); Has 33519 Blast hits to 33516 proteins in 2975 species: Archae - 937; Bacteria - 23616; Metazoa - 672; Fungi - 820; Plants - 1333; Viruses - 0; Other Eukaryotes - 6141 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      13275200..13277188
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_118753.3 → NP_194350.1  1-amino-cyclopropane-1-carboxylate synthase 7 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_194350.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9STR4
      UniProtKB/TrEMBL
      A0A5S9XW32, A0A654FSW5, A0A7G2F3T2
      Conserved Domains (1) summary
      PLN02607
      Location:6 → 447
      PLN02607; 1-aminocyclopropane-1-carboxylate synthase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9STR4.1

    Gene LinkOut

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