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    4CL8 AMP-dependent synthetase and ligase family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 833792, updated on 18-Sep-2024

    Summary

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    Official Symbol
    4CL8
    Official Full Name
    AMP-dependent synthetase and ligase family protein
    Primary source
    TAIR:AT5G38120
    Locus tag
    AT5G38120
    See related
    Araport:AT5G38120
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    MXA21.2; MXA21_2
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    Genomic context

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    See 4CL8 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    4
    Sequence:
    Chromosome: 5; NC_003076.8 (15213593..15216205)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene anti- silencing function 1b Neighboring gene HXXXD-type acyl-transferase family protein Neighboring gene nuclear factor Y, subunit C12

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis 4-COUMAROYL-COA LIGASE 8 contributes to the biosynthesis of the benzenoid ring of coenzyme Q in peroxisomes. Soubeyrand E, et al. Biochem J, 2019 Nov 29. PMID 31688904
    2. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    NM_001344230.1
    NM_123172.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables 4-coumarate-CoA ligase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables CoA-ligase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within ubiquinone biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in peroxisome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    AMP-dependent synthetase and ligase family protein
    NP_198628.2
    • AMP-dependent synthetase and ligase family protein; FUNCTIONS IN: 4-coumarate-CoA ligase activity; INVOLVED IN: metabolic process; EXPRESSED IN: 17 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: AMP-binding, conserved site (InterPro:IPR020845), AMP-dependent synthetase/ligase (InterPro:IPR000873); BEST Arabidopsis thaliana protein match is: AMP-dependent synthetase and ligase family protein (TAIR:AT1G20500.1); Has 83515 Blast hits to 76136 proteins in 3676 species: Archae - 1169; Bacteria - 53948; Metazoa - 3493; Fungi - 4649; Plants - 2738; Viruses - 1; Other Eukaryotes - 17517 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      15213593..15216205
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001344228.1 → NP_001331963.1  AMP-dependent synthetase and ligase family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UMS5, A0A1P8BFI3

    2. NM_001344229.1 → NP_001331962.1  AMP-dependent synthetase and ligase family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BFF5, A0A5S9Y901

    3. NM_123172.4 → NP_198628.2  AMP-dependent synthetase and ligase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_198628.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q84P26, Q8GXU2, Q9FF44
      UniProtKB/TrEMBL
      A0A5S9Y901
      Conserved Domains (2) summary
      cd05904
      Location:33 → 542
      4CL; 4-Coumarate-CoA Ligase (4CL)
      PLN02574
      Location:17 → 542
      PLN02574; 4-coumarate--CoA ligase-like

    4. NM_001344230.1 → NP_001331964.1  AMP-dependent synthetase and ligase family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UMS5, A0A1P8BFI3
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q84P26.2

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