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    CDF2 cycling DOF factor 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 833962, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CDF2
    Official Full Name
    cycling DOF factor 2
    Primary source
    TAIR:AT5G39660
    Locus tag
    AT5G39660
    See related
    Araport:AT5G39660
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    cycling DOF factor 2; MIJ24.16; MIJ24_16
    Summary
    Dof-type zinc finger domain-containing protein, identical to H-protein promoter binding factor-2a GI:3386546 from (Arabidopsis thaliana). Interacts with LKP2 and FKF1, but its overexpression does not change flowering time under short or long day conditions.
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    Genomic context

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    See CDF2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    2
    Sequence:
    Chromosome: 5; NC_003076.8 (15878698..15881537)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Defensin-like (DEFL) family protein Neighboring gene transmembrane protein, putative (DUF679) Neighboring gene Calcium-binding EF-hand family protein Neighboring gene ncRNA Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein Neighboring gene NAC domain containing protein 93

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Roles of Arabidopsis CDF2 in Transcriptional and Posttranscriptional Regulation of Primary MicroRNAs. Sun Z, et al. PLoS Genet, 2015 Oct. PMID 26473486, Free PMC Article
    2. Arabidopsis DOF transcription factors act redundantly to reduce CONSTANS expression and are essential for a photoperiodic flowering response. Fornara F, et al. Dev Cell, 2009 Jul. PMID 19619493
    3. The GI-CDF module of Arabidopsis affects freezing tolerance and growth as well as flowering. Fornara F, et al. Plant J, 2015 Mar. PMID 25600594, Free PMC Article
    4. FKF1 F-box protein mediates cyclic degradation of a repressor of CONSTANS in Arabidopsis. Imaizumi T, et al. Science, 2005 Jul 8. PMID 16002617
    5. Substrates related to chromatin and to RNA-dependent processes are modified by Arabidopsis SUMO isoforms that differ in a conserved residue with influence on desumoylation. Budhiraja R, et al. Plant Physiol, 2009 Mar. PMID 19151129, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. We conclude that CDF2 regulates a group of pri-miRNAs at both the transcriptional and posttranscriptional levels to maintain proper levels of their mature miRNAs to control plant development.
      Title: The Roles of Arabidopsis CDF2 in Transcriptional and Posttranscriptional Regulation of Primary MicroRNAs.
    2. Detailed expression studies followed by phenotypic assays showed that the CDFs function downstream of GI, influencing responses to freezing temperatures and growth, but are not necessary for proper clock function.
      Title: The GI-CDF module of Arabidopsis affects freezing tolerance and growth as well as flowering.
    3. Data suggest that antagonism between GIGANTEA and DOF transcription factors contributes to photoperiodic flowering by modulating an underlying diurnal rhythm in CONSTANS transcript levels [CDF2].
      Title: Arabidopsis DOF transcription factors act redundantly to reduce CONSTANS expression and are essential for a photoperiodic flowering response.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001344299.1
    NM_123328.2
    NM_180775.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables transcription cis-regulatory region binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within regulation of DNA-templated transcription TAS
    Traceable Author Statement
    more info
    		 PubMed 
    NOT involved_in regulation of timing of transition from vegetative to reproductive phase IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    cycling DOF factor 2
    NP_001318708.1
    • cycling DOF factor 2 (CDF2); CONTAINS InterPro DOMAIN/s: Zinc finger, Dof-type (InterPro:IPR003851); BEST Arabidopsis thaliana protein match is: cycling DOF factor 3 (TAIR:AT3G47500.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_851106.1
    • cycling DOF factor 2 (CDF2); CONTAINS InterPro DOMAIN/s: Zinc finger, Dof-type (InterPro:IPR003851); BEST Arabidopsis thaliana protein match is: cycling DOF factor 3 (TAIR:AT3G47500.1); Has 1150 Blast hits to 1134 proteins in 76 species: Archae - 0; Bacteria - 6; Metazoa - 18; Fungi - 6; Plants - 1095; Viruses - 0; Other Eukaryotes - 25 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      15878698..15881537
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_180775.3 → NP_851106.1  cycling DOF factor 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_851106.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q5XF25, Q93ZL5, Q9FK95
      UniProtKB/TrEMBL
      A0A178UGH8, A0A5S9Y9C9, A0A654G7F8, A0A7G2FJ88
      Conserved Domains (1) summary
      pfam02701
      Location:137 → 193
      zf-Dof; Dof domain, zinc finger

    2. NM_001344299.1 → NP_001318708.1  cycling DOF factor 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q5XF25, Q93ZL5, Q9FK95
      UniProtKB/TrEMBL
      A0A178UGH8, A0A5S9Y9C9, A0A654G7F8, A0A7G2FJ88
      Conserved Domains (1) summary
      pfam02701
      Location:137 → 193
      zf-Dof; Dof domain, zinc finger

    3. NM_123328.2 → NP_568567.1  cycling DOF factor 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568567.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q5XF25, Q93ZL5, Q9FK95
      UniProtKB/TrEMBL
      A0A178UGH8, A0A5S9Y9C9, A0A654G7F8, A0A7G2FJ88
      Conserved Domains (1) summary
      pfam02701
      Location:137 → 193
      zf-Dof; Dof domain, zinc finger
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q93ZL5.2

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