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    PUP1 purine permease 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 839717, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PUP1
    Official Full Name
    purine permease 1
    Primary source
    TAIR:AT1G28230
    Locus tag
    AT1G28230
    See related
    Araport:AT1G28230
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATPUP1; F3H9.22; F3H9_22; purine permease 1; PURINE PERMEASE 1
    Summary
    Encodes a transporter that transports purines,cytokinins and other adenine derivatives. Expressed in the leaf hydathodes where it may be involved in re-uptake of cytokinins during guttation.
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    Genomic context

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    See PUP1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    2
    Sequence:
    Chromosome: 1; NC_003070.9 (9862041..9864779, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene DNAJ heat shock family protein Neighboring gene purine permease 3 Neighboring gene strawberry notch protein (DUF616) Neighboring gene uncharacterized protein Neighboring gene Telomerase activating protein Est1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Recycling of pyridoxine (vitamin B6) by PUP1 in Arabidopsis. Szydlowski N, et al. Plant J, 2013 Jul. PMID 23551747
    2. Transport of cytokinins mediated by purine transporters of the PUP family expressed in phloem, hydathodes, and pollen of Arabidopsis. Bürkle L, et al. Plant J, 2003 Apr. PMID 12662305
    3. Border control--a membrane-linked interactome of Arabidopsis. Jones AM, et al. Science, 2014 May 16. PMID 24833385
    4. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
    5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. PUP1 is involved in the uptake of the vitamin.
      Title: Recycling of pyridoxine (vitamin B6) by PUP1 in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_102588.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables purine nucleobase transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables purine nucleobase transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables purine nucleoside transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cytokinin transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within purine nucleobase transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    purine permease 1
    NP_174144.1
    • purine permease 1 (PUP1); CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF6, transmembrane (InterPro:IPR000620), Protein of unknown function DUF250 (InterPro:IPR004853); BEST Arabidopsis thaliana protein match is: purine permease 3 (TAIR:AT1G28220.1); Has 617 Blast hits to 607 proteins in 89 species: Archae - 4; Bacteria - 97; Metazoa - 10; Fungi - 14; Plants - 377; Viruses - 0; Other Eukaryotes - 115 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      9862041..9864779 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_102588.3 → NP_174144.1  purine permease 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_174144.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FZ96, Q9M7R1
      UniProtKB/TrEMBL
      A0A178WNG8, A0A5S9W833
      Conserved Domains (2) summary
      pfam16913
      Location:16 → 334
      PUNUT; Purine nucleobase transmembrane transport
      cl23754
      Location:74 → 158
      EamA; EamA-like transporter family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FZ96.1

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