U1A spliceosomal protein U1A [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: U1A
Official Full Name: spliceosomal protein U1A
Primary source: TAIR:AT2G47580
Locus tag: AT2G47580
See related: Araport:AT2G47580
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: spliceosomal protein U1A; T30B22.12; U1SNRNP-SPECIFIC PROTEIN
Summary: encodes spliceosomal protein U1A
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Genomic context

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See U1A in Genome Data Viewer

Location:: chromosome: 2

Exon count:: 5

Sequence:: Chromosome: 2; NC_003071.7 (19517187..19518913)

Chromosome 2 - NC_003071.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

A critical role for the AtU1A spliceosomal protein in regulating alternative splicing and in determining salt tolerance.
Title: Spliceosomal protein U1A is involved in alternative splicing and salt stress tolerance in Arabidopsis thaliana.

Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_130326.3

Supported by ESTs:

Gene Ontology Provided by TAIR

Process	Evidence Code	Pubs
acts_upstream_of_or_within mRNA splicing, via spliceosome	ISS Inferred from Sequence or Structural Similarity more info	PubMed
acts_upstream_of_or_within response to salt stress	IGI Inferred from Genetic Interaction more info	PubMed

Component	Evidence Code	Pubs
part_of U1 snRNP	IDA Inferred from Direct Assay more info	PubMed
part_of U1 snRNP	ISS Inferred from Sequence or Structural Similarity more info	PubMed
located_in nucleolus	HDA more info	PubMed
located_in nucleus	HDA more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: spliceosomal protein U1A

NP_182280.1

spliceosomal protein U1A (U1A); FUNCTIONS IN: RNA binding, nucleotide binding, nucleic acid binding; INVOLVED IN: response to salt stress, nuclear mRNA splicing, via spliceosome; LOCATED IN: nucleolus, nucleus, U1 snRNP; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: RNA recognition motif, RNP-1 (InterPro:IPR000504), Nucleotide-binding, alpha-beta plait (InterPro:IPR012677); BEST Arabidopsis thaliana protein match is: U2 small nuclear ribonucleoprotein B (TAIR:AT2G30260.1); Has 2473 Blast hits to 2417 proteins in 290 species: Archae - 0; Bacteria - 37; Metazoa - 1259; Fungi - 517; Plants - 407; Viruses - 1; Other Eukaryotes - 252 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003071.7 Reference assembly

Range

19517187..19518913

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_130326.3 → NP_182280.1 spliceosomal protein U1A [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_182280.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q39244

UniProtKB/TrEMBL

A0A178VZ67, A0A5S9X7T5

Conserved Domains (2) summary

cd12246
Location:19 → 96

RRM1_U1A_like; RNA recognition motif 1 (RRM1) found in the U1A/U2B"/SNF protein family

cd12247
Location:175 → 246

RRM2_U1A_like; RNA recognition motif 2 (RRM2) found in the U1A/U2B"/SNF protein family