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    Csn3 casein kappa [ Rattus norvegicus (Norway rat) ]

    Gene ID: 29188, updated on 9-Dec-2024

    Summary

    Official Symbol
    Csn3provided by RGD
    Official Full Name
    casein kappaprovided by RGD
    Primary source
    RGD:61990
    See related
    EnsemblRapid:ENSRNOG00000001951 AllianceGenome:RGD:61990
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Csnk; Csn10
    Summary
    Predicted to be involved in lactation and protein stabilization. Predicted to be active in extracellular space. Orthologous to human CSN3 (casein kappa). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Muscle (RPKM 25.8), Testes (RPKM 4.5) and 1 other tissue See more
    Orthologs
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    Genomic context

    See Csn3 in Genome Data Viewer
    Location:
    14p21
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (20433277..20439830, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (20154032..20160585, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (21803738..21810291, complement)

    Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene calcium binding protein, spermatid associated 1 Neighboring gene mucin-5AC-like Neighboring gene uncharacterized LOC120096584 Neighboring gene follicular dendritic cell secreted protein Neighboring gene uncharacterized LOC108352727 Neighboring gene odontogenic, ameloblast associated

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in lactation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within lactation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in lactation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein stabilization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein stabilization ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in extracellular space ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_031562.2NP_113750.1  kappa-casein precursor

      See identical proteins and their annotated locations for NP_113750.1

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000014
      UniProtKB/Swiss-Prot
      P04468
      UniProtKB/TrEMBL
      A6KU13
      Related
      ENSRNOP00000002671.2, ENSRNOT00000002671.5
      Conserved Domains (1) summary
      pfam00997
      Location:22177
      Casein_kappa; Kappa casein

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086032.1 Reference GRCr8

      Range
      20433277..20439830 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)