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    ARASP chloroplastic membrane metallo proteases [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817809, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ARASP
    Official Full Name
    chloroplastic membrane metallo proteases
    Primary source
    TAIR:AT2G32480
    Locus tag
    AT2G32480
    See related
    Araport:AT2G32480
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS SERIN PROTEASE; T26B15.4; T26B15_4
    Summary
    Metalloprotease essential for plastid development. Located in the inner membrane of chloroplasts.
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    Genomic context

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    See ARASP in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    2
    Sequence:
    Chromosome: 2; NC_003071.7 (13788517..13790077, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene myb domain protein 101 Neighboring gene F-box associated ubiquitination effector family protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene miscRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A chloroplastic inner envelope membrane protease is essential for plant development. Bölter B, et al. FEBS Lett, 2006 Feb 6. PMID 16413549
    2. Sorting signals, N-terminal modifications and abundance of the chloroplast proteome. Zybailov B, et al. PLoS One, 2008 Apr 23. PMID 18431481, Free PMC Article
    3. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_128807.1
    NM_201853.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables metalloendopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metalloendopeptidase activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within chloroplast organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast inner membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    chloroplastic membrane metallo proteases
    NP_565745.1
    • ARABIDOPSIS SERIN PROTEASE (ARASP); FUNCTIONS IN: metalloendopeptidase activity; INVOLVED IN: proteolysis, chloroplast organization; LOCATED IN: chloroplast, plastid, chloroplast inner membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase M50 (InterPro:IPR008915), PDZ/DHR/GLGF (InterPro:IPR001478), Peptidase M50, putative membrane-associated zinc metallopeptidase (InterPro:IPR004387); BEST Arabidopsis thaliana protein match is: Peptidase M50 family protein (TAIR:AT1G05140.1); Has 10037 Blast hits to 7541 proteins in 2236 species: Archae - 41; Bacteria - 6710; Metazoa - 4; Fungi - 0; Plants - 70; Viruses - 0; Other Eukaryotes - 3212 (source: NCBI BLink).
    NP_973582.1
    • ARABIDOPSIS SERIN PROTEASE (ARASP); FUNCTIONS IN: metalloendopeptidase activity; INVOLVED IN: proteolysis, chloroplast organization; LOCATED IN: chloroplast, plastid, chloroplast inner membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase M50 (InterPro:IPR008915), PDZ/DHR/GLGF (InterPro:IPR001478), Peptidase M50, putative membrane-associated zinc metallopeptidase (InterPro:IPR004387); BEST Arabidopsis thaliana protein match is: Peptidase M50 family protein (TAIR:AT1G05140.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      13788517..13790077 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_201853.2 → NP_973582.1  chloroplastic membrane metallo proteases [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_973582.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A7G2EGN7, F4ITR5
      Conserved Domains (3) summary
      cd06163
      Location:88 → 399
      S2P-M50_PDZ_RseP-like; RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog ...
      cd00989
      Location:200 → 283
      PDZ_metalloprotease; PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ ...
      TIGR00054
      Location:84 → 403
      TIGR00054; RIP metalloprotease RseP

    2. NM_128807.1 → NP_565745.1  chloroplastic membrane metallo proteases [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_565745.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O80885
      UniProtKB/TrEMBL
      A0A178VYQ2, A0A654EY53
      Conserved Domains (1) summary
      TIGR00054
      Location:84 → 440
      TIGR00054; RIP metalloprotease RseP
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O80885.1

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