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    TFIIS transcript elongation factor IIS [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 818438, updated on 18-Sep-2024

    Summary

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    Official Symbol
    TFIIS
    Official Full Name
    transcript elongation factor IIS
    Primary source
    TAIR:AT2G38560
    Locus tag
    AT2G38560
    See related
    Araport:AT2G38560
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    RDO2; REDUCED DORMANCY 2; T6A23.24; T6A23_24; transcript elongation factor IIS
    Summary
    Encodes RNA polymerase II transcript elongation factor TFIIS. Complements yeast TFIIS mutation. Mutant plants display essentially normal development, but they flower slightly earlier than the wild type and show clearly reduced seed dormancy.
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    Genomic context

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    See TFIIS in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    2
    Sequence:
    Chromosome: 2; NC_003071.7 (16134543..16136695)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene lipid transfer protein 1 Neighboring gene Transmembrane proteins 14C Neighboring gene uncharacterized protein Neighboring gene Mitochondrial ATP synthase D chain-related protein Neighboring gene F-box and associated interaction domains-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Elongation factor TFIIS is essential for heat stress adaptation in plants. Szádeczky-Kardoss I, et al. Nucleic Acids Res, 2022 Feb 28. PMID 35100405, Free PMC Article
    2. Identification of the Arabidopsis REDUCED DORMANCY 2 gene uncovers a role for the polymerase associated factor 1 complex in seed dormancy. Liu Y, et al. PLoS One, 2011. PMID 21799800, Free PMC Article
    3. Arabidopsis mutants with a reduced seed dormancy. Léon-Kloosterziel KM, et al. Plant Physiol, 1996 Jan. PMID 8587986, Free PMC Article
    4. The seed dormancy defect of Arabidopsis mutants lacking the transcript elongation factor TFIIS is caused by reduced expression of the DOG1 gene. Mortensen SA, et al. FEBS Lett, 2014 Jan 3. PMID 24252221
    5. Reduced expression of the DOG1 gene in Arabidopsis mutant seeds lacking the transcript elongation factor TFIIS. Mortensen SA, et al. FEBS Lett, 2011 Jun 23. PMID 21569772

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Elongation factor TFIIS is essential for heat stress adaptation in plants.
      Title: Elongation factor TFIIS is essential for heat stress adaptation in plants.
    2. HUB1, RDO2 and VIP5 are involved in the regulation of both flowering time and seed dormancy. [RDO2]
      Title: Identification of the Arabidopsis REDUCED DORMANCY 2 gene uncovers a role for the polymerase associated factor 1 complex in seed dormancy.
    3. Data show that the down-regulation of DOG1 expression causes the seed dormancy phenotype of tfIIs mutants.
      Title: The seed dormancy defect of Arabidopsis mutants lacking the transcript elongation factor TFIIS is caused by reduced expression of the DOG1 gene.
    4. suggesting that down-regulation of DOG1 expression is involved in the seed dormancy phenotype of tfIIs mutants
      Title: Reduced expression of the DOG1 gene in Arabidopsis mutant seeds lacking the transcript elongation factor TFIIS.
    5. TFIIS(-/-) plants display essentially normal development, but they flower slightly earlier than control plants and show clearly reduced seed dormancy.
      Title: Transcript elongation factor TFIIS is involved in arabidopsis seed dormancy.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_129413.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within negative regulation of flower development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of transcription elongation by RNA polymerase II IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to gibberellin IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in response to heat IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within seed dormancy process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within seed germination IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in transcription elongation by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    NOT located_in cytosol RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    transcript elongation factor IIS
    NP_181390.1
    • transcript elongation factor IIS (TFIIS); CONTAINS InterPro DOMAIN/s: Zinc finger, TFIIS-type (InterPro:IPR001222), Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type (InterPro:IPR003617), Transcription elongation factor S-II, central domain (InterPro:IPR003618), Transcription factor IIS, N-terminal (InterPro:IPR017923), Transcription elongation factor S-IIM (InterPro:IPR017890), Transcription elongation factor, IIS (InterPro:IPR016492), Transcription elongation factor, TFIIS (InterPro:IPR006289), Transcription elongation factor, TFIIS/elongin A/CRSP70, N-terminal (InterPro:IPR010990); BEST Arabidopsis thaliana protein match is: F-box family protein (TAIR:AT2G42730.1); Has 1858 Blast hits to 1830 proteins in 294 species: Archae - 58; Bacteria - 2; Metazoa - 702; Fungi - 370; Plants - 279; Viruses - 52; Other Eukaryotes - 395 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      16134543..16136695
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_129413.4 → NP_181390.1  transcript elongation factor IIS [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_181390.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8VXZ6, Q9ZVH8
      UniProtKB/TrEMBL
      A0A178VY86, A0A5S9X576
      Conserved Domains (1) summary
      TIGR01385
      Location:21 → 378
      TFSII; transcription elongation factor S-II
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9ZVH8.1

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