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    CHR8 chromatin remodeling 8 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 816391, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CHR8
    Official Full Name
    chromatin remodeling 8
    Primary source
    TAIR:AT2G18760
    Locus tag
    AT2G18760
    See related
    Araport:AT2G18760
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    chromatin remodeling 8; ERCC6; MSF3.14; MSF3_14; RAD26
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    Genomic context

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    See CHR8 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    8
    Sequence:
    Chromosome: 2; NC_003071.7 (8128706..8134401)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Small nuclear ribonucleoprotein family protein Neighboring gene Calmodulin-binding protein Neighboring gene P-loop containing nucleoside triphosphate hydrolases superfamily protein Neighboring gene F-box and associated interaction domains-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Involvement of the Arabidopsis SWI2/SNF2 chromatin remodeling gene family in DNA damage response and recombination. Shaked H, et al. Genetics, 2006 Jun. PMID 16547115, Free PMC Article
    2. Dynamic response of plant genome to ultraviolet radiation and other genotoxic stresses. Molinier J, et al. Mutat Res, 2005 Apr 1. PMID 15748650
    3. The chromatin remodeler ERCC6 and the histone chaperone NAP1 are involved in apurinic/apyrimidinic endonuclease-mediated DNA repair. Fan T, et al. Plant Cell, 2024 May 29. PMID 38367203, Free PMC Article
    4. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article
    5. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The chromatin remodeler ERCC6 and the histone chaperone NAP1 are involved in apurinic/apyrimidinic endonuclease-mediated DNA repair.
      Title: The chromatin remodeler ERCC6 and the histone chaperone NAP1 are involved in apurinic/apyrimidinic endonuclease-mediated DNA repair.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001335605.1
    NM_001335609.1
    NM_001335610.1
    NM_127432.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATP-dependent chromatin remodeler activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA damage response IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within DNA repair IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to gamma radiation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    chromatin remodeling 8
    NP_001318246.1
    • chromatin remodeling 8 (CHR8); FUNCTIONS IN: helicase activity, DNA binding, ATP binding, nucleic acid binding; INVOLVED IN: DNA repair, response to gamma radiation; EXPRESSED IN: 15 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: DEAD-like helicase, N-terminal (InterPro:IPR014001), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021), SNF2-related (InterPro:IPR000330); BEST Arabidopsis thaliana protein match is: chromatin remodeling 24 (TAIR:AT5G63950.1); Has 17230 Blast hits to 14463 proteins in 1653 species: Archae - 99; Bacteria - 4180; Metazoa - 3846; Fungi - 4219; Plants - 1677; Viruses - 118; Other Eukaryotes - 3091 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      8128706..8134401
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001335607.1 → NP_001324142.1  chromatin remodeling 8 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AZA4, A0A654EVB3

    2. NM_001335606.1 → NP_001324143.1  chromatin remodeling 8 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9ZV43
      UniProtKB/TrEMBL
      A0A178VUI7, A0A654EVB3
      Conserved Domains (2) summary
      COG0553
      Location:377 → 893
      HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
      cd18000
      Location:385 → 593
      DEXHc_ERCC6; DEXH-box helicase domain of ERCC6

    3. NM_001335608.1 → NP_001324146.1  chromatin remodeling 8 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9ZV43
      UniProtKB/TrEMBL
      A0A178VUI7, A0A654EVB3
      Conserved Domains (2) summary
      COG0553
      Location:377 → 893
      HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
      cd18000
      Location:385 → 593
      DEXHc_ERCC6; DEXH-box helicase domain of ERCC6

    4. NM_001335605.1 → NP_001318246.1  chromatin remodeling 8 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9ZV43
      UniProtKB/TrEMBL
      A0A178VUI7, A0A654EVB3
      Conserved Domains (2) summary
      COG0553
      Location:377 → 893
      HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
      cd18000
      Location:385 → 593
      DEXHc_ERCC6; DEXH-box helicase domain of ERCC6

    5. NM_001335609.1 → NP_001324145.1  chromatin remodeling 8 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9ZV43
      UniProtKB/TrEMBL
      A0A178VUI7, A0A654EVB3
      Conserved Domains (2) summary
      COG0553
      Location:377 → 893
      HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
      cd18000
      Location:385 → 593
      DEXHc_ERCC6; DEXH-box helicase domain of ERCC6

    6. NM_001335610.1 → NP_001324144.1  chromatin remodeling 8 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9ZV43
      UniProtKB/TrEMBL
      A0A178VUI7, A0A654EVB3
      Conserved Domains (2) summary
      COG0553
      Location:377 → 893
      HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
      cd18000
      Location:385 → 593
      DEXHc_ERCC6; DEXH-box helicase domain of ERCC6

    7. NM_127432.2 → NP_179466.1  chromatin remodeling 8 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_179466.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9ZV43
      UniProtKB/TrEMBL
      A0A178VUI7, A0A654EVB3
      Conserved Domains (2) summary
      COG0553
      Location:377 → 893
      HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
      cd18000
      Location:385 → 593
      DEXHc_ERCC6; DEXH-box helicase domain of ERCC6
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9ZV43.1

    Gene LinkOut

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