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    SPL2 E3 Ubiquitin ligase family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 841855, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SPL2
    Official Full Name
    E3 Ubiquitin ligase family protein
    Primary source
    TAIR:AT1G54150
    Locus tag
    AT1G54150
    See related
    Araport:AT1G54150
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F15I1.25; F15I1_25; SP1-like 2
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    Genomic context

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    See SPL2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    6
    Sequence:
    Chromosome: 1; NC_003070.9 (20215395..20217489)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene RELA/SPOT homolog 3 Neighboring gene TATA binding protein associated factor 21kDa subunit Neighboring gene ncRNA Neighboring gene nuclear factor Y, subunit A5 Neighboring gene CTC-interacting domain 3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. NERF encodes a RING E3 ligase important for drought resistance and enhances the expression of its antisense gene NFYA5 in Arabidopsis. Gao W, et al. Nucleic Acids Res, 2015 Jan. PMID 25514924, Free PMC Article
    2. E3 ubiquitin ligase SP1 regulates peroxisome biogenesis in Arabidopsis. Pan R, et al. Proc Natl Acad Sci U S A, 2016 Nov 15. PMID 27799549, Free PMC Article
    3. Chloroplast biogenesis is regulated by direct action of the ubiquitin-proteasome system. Ling Q, et al. Science, 2012 Nov 2. PMID 23118188
    4. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Analysis of NERF knock-down plants and NERF overexpression lines showed that NERF is important for controlling stomatal aperture and drought resistance. [NERF]
      Title: NERF encodes a RING E3 ligase important for drought resistance and enhances the expression of its antisense gene NFYA5 in Arabidopsis.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    NM_104293.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ubiquitin-protein transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in organelle organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast envelope IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    E3 Ubiquitin ligase family protein
    NP_564653.1
    • E3 Ubiquitin ligase family protein; FUNCTIONS IN: zinc ion binding; LOCATED IN: endomembrane system; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Zinc finger, RING-type (InterPro:IPR001841), E3 Ubiquitin ligase (InterPro:IPR022170); BEST Arabidopsis thaliana protein match is: E3 Ubiquitin ligase family protein (TAIR:AT1G59560.1); Has 1960 Blast hits to 1959 proteins in 225 species: Archae - 0; Bacteria - 0; Metazoa - 1182; Fungi - 34; Plants - 350; Viruses - 140; Other Eukaryotes - 254 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      20215395..20217489
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001333632.1 → NP_001320570.1  E3 Ubiquitin ligase family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AN81

    2. NM_104293.4 → NP_564653.1  E3 Ubiquitin ligase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_564653.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SYH3
      UniProtKB/TrEMBL
      A0A178WL91, A0A5S9WPM0
      Conserved Domains (3) summary
      cd00162
      Location:331 → 370
      RING_Ubox; RING-HC finger (C3HC4-type) [structural motif]
      pfam12483
      Location:140 → 286
      GIDE; E3 Ubiquitin ligase
      pfam13920
      Location:327 → 377
      zf-C3HC4_3; Zinc finger, C3HC4 type (RING finger)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SYH3.1

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