U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    CSTF64 cleavage stimulating factor 64 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 843510, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    CSTF64
    Official Full Name
    cleavage stimulating factor 64
    Primary source
    TAIR:AT1G71800
    Locus tag
    AT1G71800
    See related
    Araport:AT1G71800
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    cleavage stimulating factor 64; F14O23.18; F14O23_18
    Summary
    RNA 3'-end#Aeiprocessing factor of antisense FLC transcript. Mediates silencing of the floral repressor gene FLC.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See CSTF64 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    11
    Sequence:
    Chromosome: 1; NC_003070.9 (26999374..27002458)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene WD repeat protein Neighboring gene Subunits of heterodimeric actin filament capping protein Capz superfamily Neighboring gene Protein kinase superfamily protein Neighboring gene SEC6 Neighboring gene ncRNA Neighboring gene somatic embryogenesis receptor-like kinase 1

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Modulation of Auxin Signaling and Development by Polyadenylation Machinery. Zeng W, et al. Plant Physiol, 2019 Feb. PMID 30487141, Free PMC Article
    2. Cloning and characterization of Arabidopsis homologues of the animal CstF complex that regulates 3' mRNA cleavage and polyadenylation. Yao Y, et al. J Exp Bot, 2002 Nov. PMID 12379796
    3. Targeted 3' processing of antisense transcripts triggers Arabidopsis FLC chromatin silencing. Liu F, et al. Science, 2010 Jan 1. PMID 19965720
    4. The interaction between two Arabidopsis polyadenylation factor subunits involves an evolutionarily-conserved motif and has implications for the assembly and function of the polyadenylation complex. Addepalli B, et al. Protein Pept Lett, 2008. PMID 18221017
    5. An Arabidopsis Fip1 homolog interacts with RNA and provides conceptual links with a number of other polyadenylation factor subunits. Forbes KP, et al. J Biol Chem, 2006 Jan 6. PMID 16282318

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. CstF64, an CstF77 interacting protein, is also involved in auxin signaling.
      Title: Modulation of Auxin Signaling and Development by Polyadenylation Machinery.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help
    NM_105838.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within RNA 3'-end processing IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in antisense RNA metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within developmental growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mRNA 3'-end processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within negative regulation of DNA-templated transcription IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in post-transcriptional gene silencing IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulatory ncRNA-mediated gene silencing IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    cleavage stimulating factor 64
    NP_177325.2
    • cleavage stimulating factor 64 (CSTF64); CONTAINS InterPro DOMAIN/s: RNA recognition motif, RNP-1 (InterPro:IPR000504), Nucleotide-binding, alpha-beta plait (InterPro:IPR012677); BEST Arabidopsis thaliana protein match is: RNA-binding (RRM/RBD/RNP motifs) family protein (TAIR:AT4G00830.3); Has 21430 Blast hits to 18533 proteins in 865 species: Archae - 10; Bacteria - 1688; Metazoa - 9678; Fungi - 3064; Plants - 4656; Viruses - 0; Other Eukaryotes - 2334 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      26999374..27002458
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_105838.5 → NP_177325.2  cleavage stimulating factor 64 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_177325.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LKG6, Q9M9G6
      UniProtKB/TrEMBL
      A0A178W5F3, A0A5S9WTR3
      Conserved Domains (5) summary
      TIGR01628
      Location:11 → 318
      PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
      cd12671
      Location:11 → 85
      RRM_CSTF2_CSTF2T; RNA recognition motif in cleavage stimulation factor subunit 2 (CSTF2), cleavage stimulation factor subunit 2 tau variant (CSTF2T) and similar proteins
      pfam09770
      Location:222 → 433
      PAT1; Topoisomerase II-associated protein PAT1
      pfam14304
      Location:419 → 454
      CSTF_C; Transcription termination and cleavage factor C-terminal
      pfam14327
      Location:160 → 228
      CSTF2_hinge; Hinge domain of cleavage stimulation factor subunit 2
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9M9G6.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools