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    PPC4 phosphoenolpyruvate carboxylase 4 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 843206, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PPC4
    Official Full Name
    phosphoenolpyruvate carboxylase 4
    Primary source
    TAIR:AT1G68750
    Locus tag
    AT1G68750
    See related
    Araport:AT1G68750
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATPPC4; F14K14.14; F14K14_14; phosphoenolpyruvate carboxylase 4
    Summary
    Encodes one of four Arabidopsis phosphoenolpyruvate (PEP) carboxylase proteins. But, it is more similar to bacterial PEP carboxylase than plant PEP carboxylase. Efforts to express this enzyme and to demonstrate its enzymatic activity in E.coli failed.
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    Genomic context

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    See PPC4 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    20
    Sequence:
    Chromosome: 1; NC_003070.9 (25822716..25828147, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene miscRNA Neighboring gene EXS (ERD1/XPR1/SYG1) family protein Neighboring gene tRNA-Pro Neighboring gene nudix hydrolase 1 Neighboring gene Putative membrane lipoprotein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification and expression analysis of a gene encoding a bacterial-type phosphoenolpyruvate carboxylase from Arabidopsis and rice. Sánchez R, et al. Plant Physiol, 2003 Jun. PMID 12805623, Free PMC Article
    2. Bacterial- and plant-type phosphoenolpyruvate carboxylase polypeptides interact in the hetero-oligomeric Class-2 PEPC complex of developing castor oil seeds. Gennidakis S, et al. Plant J, 2007 Dec. PMID 17894783
    3. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article
    4. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_105548.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    NOT enables phosphoenolpyruvate carboxylase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables phosphoenolpyruvate carboxylase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within tricarboxylic acid cycle ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    phosphoenolpyruvate carboxylase 4
    NP_177043.2
    • phosphoenolpyruvate carboxylase 4 (PPC4); CONTAINS InterPro DOMAIN/s: Pyruvate/Phosphoenolpyruvate kinase, catalytic core (InterPro:IPR015813), Phosphoenolpyruvate carboxylase, active site (InterPro:IPR018129), Phosphoenolpyruvate carboxylase (InterPro:IPR001449), Phosphoenolpyruvate carboxylase, C-terminal region (InterPro:IPR021135); BEST Arabidopsis thaliana protein match is: phosphoenolpyruvate carboxylase 1 (TAIR:AT1G53310.3); Has 9944 Blast hits to 6686 proteins in 1878 species: Archae - 54; Bacteria - 5038; Metazoa - 4; Fungi - 0; Plants - 1854; Viruses - 0; Other Eukaryotes - 2994 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      25822716..25828147 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_105548.5 → NP_177043.2  phosphoenolpyruvate carboxylase 4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_177043.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8GVE8, Q9CA39, Q9SX35
      UniProtKB/TrEMBL
      A0A178W7Q9, A0A5S9WT09, A0A654ENX1
      Conserved Domains (1) summary
      PRK00009
      Location:19 → 1032
      PRK00009; phosphoenolpyruvate carboxylase; Reviewed
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8GVE8.1

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