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    MNS3 alpha-mannosidase 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 839879, updated on 18-Sep-2024

    Summary

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    Official Symbol
    MNS3
    Official Full Name
    alpha-mannosidase 3
    Primary source
    TAIR:AT1G30000
    Locus tag
    AT1G30000
    See related
    Araport:AT1G30000
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    alpha-mannosidase 3; T1P2.10; T1P2_10
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    Genomic context

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    See MNS3 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    6
    Sequence:
    Chromosome: 1; NC_003070.9 (10509156..10512558, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene choice-of-anchor C domain protein, putative (Protein of unknown function, DUF642) Neighboring gene prefoldin 6 Neighboring gene Intron maturase, type II family protein Neighboring gene hypothetical protein (Protein of unknown function, DUF538) Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A signal motif retains Arabidopsis ER-α-mannosidase I in the cis-Golgi and prevents enhanced glycoprotein ERAD. Schoberer J, et al. Nat Commun, 2019 Aug 16. PMID 31420549, Free PMC Article
    2. Class I alpha-mannosidases are required for N-glycan processing and root development in Arabidopsis thaliana. Liebminger E, et al. Plant Cell, 2009 Dec. PMID 20023195, Free PMC Article
    3. Separating Golgi Proteins from Cis to Trans Reveals Underlying Properties of Cisternal Localization. Parsons HT, et al. Plant Cell, 2019 Sep. PMID 31266899, Free PMC Article
    4. Mapping the Arabidopsis organelle proteome. Dunkley TP, et al. Proc Natl Acad Sci U S A, 2006 Apr 25. PMID 16618929, Free PMC Article
    5. Isolation and proteomic characterization of the Arabidopsis Golgi defines functional and novel components involved in plant cell wall biosynthesis. Parsons HT, et al. Plant Physiol, 2012 May. PMID 22430844, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    NM_001332879.1
    NM_102740.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables alpha-mannosidase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mannosyl-oligosaccharide 1,2-alpha-mannosidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within N-glycan processing IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein glycosylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within root development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus HDA PubMed 
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in Golgi apparatus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in Golgi medial cisterna HDA PubMed 
    located_in endosome HDA PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in trans-Golgi network HDA PubMed 

    General protein information

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    Preferred Names
    alpha-mannosidase 3
    NP_564345.1
    • alpha-mannosidase 3 (MNS3); CONTAINS InterPro DOMAIN/s: Glycoside hydrolase, family 47 (InterPro:IPR001382); BEST Arabidopsis thaliana protein match is: alpha-mannosidase 2 (TAIR:AT3G21160.1); Has 2086 Blast hits to 1880 proteins in 193 species: Archae - 0; Bacteria - 12; Metazoa - 798; Fungi - 875; Plants - 191; Viruses - 0; Other Eukaryotes - 210 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      10509156..10512558 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_102740.3 → NP_564345.1  alpha-mannosidase 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_564345.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q93Y37, Q9C8R9
      UniProtKB/TrEMBL
      A0A178WR43, A0A5S9WFE4, A0A7G2DYY7
      Conserved Domains (1) summary
      pfam01532
      Location:135 → 620
      Glyco_hydro_47; Glycosyl hydrolase family 47

    2. NM_001332879.1 → NP_001320239.1  alpha-mannosidase 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AM79, A0A7G2DYY7
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q93Y37.1

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