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    Calcium-binding EF-hand family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 843997, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Calcium-binding EF-hand family protein
    Primary source
    TAIR:AT1G76640
    Locus tag
    AT1G76640
    See related
    Araport:AT1G76640
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    CALMODULIN LIKE 39; CML39; F28O16.1; F28O16_1
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    1
    Sequence:
    Chromosome: 1; NC_003070.9 (28765254..28765866, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Serine/Threonine-kinase, putative (Protein of unknown function, DUF547) Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein Neighboring gene calmodulin-like 38 Neighboring gene hydroxyproline-rich glycoprotein family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The calmodulin-like protein, CML39, is involved in regulating seed development, germination, and fruit development in Arabidopsis. Midhat U, et al. Plant Mol Biol, 2018 Mar. PMID 29372457
    2. Geminivirus AL2 protein induces expression of, and interacts with, a calmodulin-like gene, an endogenous regulator of gene silencing. Yong Chung H, et al. Virology, 2014 Jul. PMID 25010276
    3. The Arabidopsis calmodulin-like protein, CML39, functions during early seedling establishment. Bender KW, et al. Plant J, 2013 Nov. PMID 24033804
    4. Developmental and stimulus-induced expression patterns of Arabidopsis calmodulin-like genes CML37, CML38 and CML39. Vanderbeld B, et al. Plant Mol Biol, 2007 Aug. PMID 17579812
    5. A histochemical reporter system to study extracellular ATP response in plants. Sowders JM, et al. Front Plant Sci, 2023. PMID 37332691, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. CML39 serves as an important Ca(2+) sensor during ovule and seed development, as well as during germination and seedling establishment.
      Title: The calmodulin-like protein, CML39, is involved in regulating seed development, germination, and fruit development in Arabidopsis.
    2. Tomato golden mosaic virus AL2 may act to sequester Arabidopsis CLM39 in the nucleus to prevent targeting of AL2 for degradation.
      Title: Geminivirus AL2 protein induces expression of, and interacts with, a calmodulin-like gene, an endogenous regulator of gene silencing.
    3. CML39 functions as a Ca2+ sensor and plays an important role in the transduction of light signals that promote seedling establishment
      Title: The Arabidopsis calmodulin-like protein, CML39, functions during early seedling establishment.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    NM_106314.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables calcium ion binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular response to hypoxia HEP PubMed 
    involved_in response to ATP IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Calcium-binding EF-hand family protein
    NP_177790.1
    • Calcium-binding EF-hand family protein; CONTAINS InterPro DOMAIN/s: EF-Hand 1, calcium-binding site (InterPro:IPR018247), EF-HAND 2 (InterPro:IPR018249), EF-hand-like domain (InterPro:IPR011992), Calcium-binding EF-hand (InterPro:IPR002048), EF-hand (InterPro:IPR018248); BEST Arabidopsis thaliana protein match is: calmodulin-like 38 (TAIR:AT1G76650.3); Has 14790 Blast hits to 11980 proteins in 1260 species: Archae - 1; Bacteria - 39; Metazoa - 6093; Fungi - 2725; Plants - 3859; Viruses - 2; Other Eukaryotes - 2071 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      28765254..28765866 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_106314.2 → NP_177790.1  Calcium-binding EF-hand family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_177790.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SRE7
      UniProtKB/TrEMBL
      A0A178W715, A0A5S9WV11
      Conserved Domains (1) summary
      PTZ00184
      Location:17 → 158
      PTZ00184; calmodulin; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SRE7.1

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