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    IRT3 iron regulated transporter 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 842387, updated on 18-Sep-2024

    Summary

    Official Symbol
    IRT3
    Official Full Name
    iron regulated transporter 3
    Primary source
    TAIR:AT1G60960
    Locus tag
    AT1G60960
    See related
    Araport:AT1G60960
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATIRT3; iron regulated transporter 3; IRON REGULATED TRANSPORTER 3; T7P1.10; T7P1_10
    Summary
    Encodes a plasma membrane localized zinc/iron transporter.
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    Genomic context

    See IRT3 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    3
    Sequence:
    Chromosome: 1; NC_003070.9 (22445299..22447299, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene SNF1-related protein kinase 2.10 Neighboring gene 2Fe-2S ferredoxin-like superfamily protein Neighboring gene SNARE-like superfamily protein Neighboring gene gibberellin 20-oxidase 4

    General gene information

    NM_001333923.1
    NM_104776.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables iron ion transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables metal ion transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables zinc ion transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables zinc ion transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
     
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
     
    located_in plant-type vacuole HDA PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
     

    General protein information

    Preferred Names
    iron regulated transporter 3
    NP_564766.1
    • iron regulated transporter 3 (IRT3); FUNCTIONS IN: cation transmembrane transporter activity, zinc ion transmembrane transporter activity, metal ion transmembrane transporter activity, iron ion transmembrane transporter activity; INVOLVED IN: cation transport, zinc ion transport, response to nematode, iron ion transport, metal ion transport; LOCATED IN: plasma membrane, membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: Zinc/iron permease, fungal/plant (InterPro:IPR004698), Zinc/iron permease (InterPro:IPR003689); BEST Arabidopsis thaliana protein match is: zinc transporter 4 precursor (TAIR:AT1G10970.1); Has 3842 Blast hits to 3068 proteins in 499 species: Archae - 2; Bacteria - 683; Metazoa - 1421; Fungi - 659; Plants - 616; Viruses - 7; Other Eukaryotes - 454 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      22445299..22447299 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001333922.1NP_001321605.1  iron regulated transporter 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8ARE2
    2. NM_104776.5NP_564766.1  iron regulated transporter 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_564766.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LE59, Q8W244, Q9C957
      UniProtKB/TrEMBL
      A0A178WHL0, A0A5S9WN65
      Conserved Domains (1) summary
      TIGR00820
      Location:46425
      zip; ZIP zinc/iron transport family
    3. NM_001333923.1NP_001321604.1  iron regulated transporter 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8ARJ0, A0A5S9WN65