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    UGE3 UDP-D-glucose/UDP-D-galactose 4-epimerase 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 842622, updated on 18-Sep-2024

    Summary

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    Official Symbol
    UGE3
    Official Full Name
    UDP-D-glucose/UDP-D-galactose 4-epimerase 3
    Primary source
    TAIR:AT1G63180
    Locus tag
    AT1G63180
    See related
    Araport:AT1G63180
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F16M19.8; F16M19_8; UDP-D-glucose/UDP-D-galactose 4-epimerase 3
    Summary
    Encodes a protein with UDP-D-glucose 4-epimerase activity. Involved in pollen development.
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    Genomic context

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    See UGE3 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    9
    Sequence:
    Chromosome: 1; NC_003070.9 (23427405..23429652, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein Neighboring gene replication factor C 2 Neighboring gene Zinc finger, C3HC4 type (RING finger) family protein Neighboring gene Cystatin/monellin superfamily protein Neighboring gene Cystatin/monellin superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Bifunctional cytosolic UDP-glucose 4-epimerases catalyse the interconversion between UDP-D-xylose and UDP-L-arabinose in plants. Kotake T, et al. Biochem J, 2009 Nov 11. PMID 19754426
    2. UDP-glucose 4-epimerase isoforms UGE2 and UGE4 cooperate in providing UDP-galactose for cell wall biosynthesis and growth of Arabidopsis thaliana. Rösti J, et al. Plant Cell, 2007 May. PMID 17496119, Free PMC Article
    3. Distinct properties of the five UDP-D-glucose/UDP-D-galactose 4-epimerase isoforms of Arabidopsis thaliana. Barber C, et al. J Biol Chem, 2006 Jun 23. PMID 16644739
    4. Proximity labeling of protein complexes and cell-type-specific organellar proteomes in Arabidopsis enabled by TurboID. Mair A, et al. Elife, 2019 Sep 19. PMID 31535972, Free PMC Article
    5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001334071.1
    NM_104996.6

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables UDP-arabinose 4-epimerase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables UDP-glucose 4-epimerase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables UDP-glucose 4-epimerase activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables protein dimerization activity IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in UDP-L-arabinose biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in capsule polysaccharide biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in galactose metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within pollen development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    UDP-D-glucose/UDP-D-galactose 4-epimerase 3
    NP_564811.1
    • UDP-D-glucose/UDP-D-galactose 4-epimerase 3 (UGE3); CONTAINS InterPro DOMAIN/s: NAD-dependent epimerase/dehydratase (InterPro:IPR001509), NAD(P)-binding domain (InterPro:IPR016040), UDP-glucose 4-epimerase (InterPro:IPR005886); BEST Arabidopsis thaliana protein match is: UDP-D-glucose/UDP-D-galactose 4-epimerase 1 (TAIR:AT1G12780.1); Has 41147 Blast hits to 41136 proteins in 2978 species: Archae - 810; Bacteria - 24610; Metazoa - 646; Fungi - 484; Plants - 1052; Viruses - 38; Other Eukaryotes - 13507 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      23427405..23429652 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_104996.6 → NP_564811.1  UDP-D-glucose/UDP-D-galactose 4-epimerase 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_564811.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LDN8, Q9CAM5
      UniProtKB/TrEMBL
      A0A178WIC1, A0A5S9WP00, A0A654EAD4
      Conserved Domains (1) summary
      PLN02240
      Location:2 → 351
      PLN02240; UDP-glucose 4-epimerase

    2. NM_001334071.1 → NP_001321118.1  UDP-D-glucose/UDP-D-galactose 4-epimerase 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8APY6, A0A654EAD4
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8LDN8.1

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