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    AHP4 HPT phosphotransmitter 4 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 820883, updated on 18-Sep-2024

    Summary

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    Official Symbol
    AHP4
    Official Full Name
    HPT phosphotransmitter 4
    Primary source
    TAIR:AT3G16360
    Locus tag
    AT3G16360
    See related
    Araport:AT3G16360
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    HPT phosphotransmitter 4; T2O4.20
    Summary
    Encodes AHP4, a histidine-containing phosphotransmitter involved in Histidine (His)-to-Aspartate (Asp) phosphorelay signal transduction. AHP4 is one of the six Arabidopsis thaliana histidine phosphotransfer proteins (AHPs). AHPs function as redundant positive regulators of cytokinin signaling. Members of the AHP gene family include: AT3G21510 (AHP1), AT3G29350 (AHP2), AT5G39340 (AHP3), AT3G16360 (AHP4), AT1G03430 (AHP5) and AT1G80100 (AHP6).
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    Genomic context

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    See AHP4 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    6
    Sequence:
    Chromosome: 3; NC_003074.8 (5554197..5555789)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Homeodomain-like superfamily protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene GDSL-like Lipase/Acylhydrolase superfamily protein Neighboring gene poly(A) binding protein 6 Neighboring gene nitrile specifier protein 3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis histidine-containing phosphotransfer factor 4 (AHP4) negatively regulates secondary wall thickening of the anther endothecium during flowering. Jung KW, et al. Mol Cells, 2008 Apr 30. PMID 18413999
    2. Compilation and characterization of histidine-containing phosphotransmitters implicated in His-to-Asp phosphorelay in plants: AHP signal transducers of Arabidopsis thaliana. Suzuki T, et al. Biosci Biotechnol Biochem, 2000 Nov. PMID 11193423
    3. The Arabidopsis histidine phosphotransfer proteins are redundant positive regulators of cytokinin signaling. Hutchison CE, et al. Plant Cell, 2006 Nov. PMID 17122069, Free PMC Article
    4. Histidine-containing phosphotransfer (HPt) signal transducers implicated in His-to-Asp phosphorelay in Arabidopsis. Suzuki T, et al. Plant Cell Physiol, 1998 Dec. PMID 10050311
    5. Characterization of genes for two-component phosphorelay mediators with a single HPt domain in Arabidopsis thaliana. Miyata S, et al. FEBS Lett, 1998 Oct 16. PMID 9804162

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. AHP4 negatively regulates thickening of the secondary cell wall of the anther endothecium, and provides new insight into the role of cytokinins in formation of secondary cell walls via the action of AHP4.
      Title: Arabidopsis histidine-containing phosphotransfer factor 4 (AHP4) negatively regulates secondary wall thickening of the anther endothecium during flowering.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_112507.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables histidine phosphotransfer kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables histidine phosphotransfer kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cytokinin-activated signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within phosphorelay signal transduction system ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    acts_upstream_of_or_within phosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of cytokinin-activated signaling pathway IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within signal transduction IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    HPT phosphotransmitter 4
    NP_001189912.1
    • HPT phosphotransmitter 4 (AHP4); CONTAINS InterPro DOMAIN/s: Signal transduction histidine kinase, phosphotransfer (Hpt) domain (InterPro:IPR008207); BEST Arabidopsis thaliana protein match is: histidine-containing phosphotransmitter 2 (TAIR:AT3G29350.1).
    NP_566544.1
    • HPT phosphotransmitter 4 (AHP4); CONTAINS InterPro DOMAIN/s: Signal transduction histidine kinase, phosphotransfer (Hpt) domain (InterPro:IPR008207); BEST Arabidopsis thaliana protein match is: histidine-containing phosphotransmitter 2 (TAIR:AT3G29350.1); Has 335 Blast hits to 334 proteins in 65 species: Archae - 0; Bacteria - 41; Metazoa - 0; Fungi - 26; Plants - 266; Viruses - 0; Other Eukaryotes - 2 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      5554197..5555789
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001202983.2 → NP_001189912.1  HPT phosphotransmitter 4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001189912.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178V965, A0A384KT90, A0A5S9XCN7, A0A654F7S4, F4J1I8
      Conserved Domains (1) summary
      pfam01627
      Location:39 → 122
      Hpt; Hpt domain

    2. NM_112507.1 → NP_566544.1  HPT phosphotransmitter 4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566544.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O04321, Q9LU15
      UniProtKB/TrEMBL
      A0A5S9XCN7, A0A654F7S4
      Conserved Domains (1) summary
      pfam01627
      Location:33 → 116
      Hpt; Hpt domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LU15.2

    Gene LinkOut

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