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    MEE31 Mannose-6-phosphate isomerase, type I [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 820656, updated on 18-Sep-2024

    Summary

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    Official Symbol
    MEE31
    Official Full Name
    Mannose-6-phosphate isomerase, type I
    Primary source
    TAIR:AT3G02570
    Locus tag
    AT3G02570
    See related
    Araport:AT3G02570
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F16B3.20; F16B3_20; MATERNAL EFFECT EMBRYO ARREST 31; PHOSPHOMANNOSE ISOMERASE 1; PMI1
    Summary
    Encodes a protein with phosphomannose isomerase activity.
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    Genomic context

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    See MEE31 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    5
    Sequence:
    Chromosome: 3; NC_003074.8 (543346..545602, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene LOB domain-containing protein 41 Neighboring gene uncharacterized protein Neighboring gene Ribosomal protein S7e family protein Neighboring gene sterol 1 Neighboring gene Fatty acid hydroxylase superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Maternal Embryo Effect Arrest 31 (MEE31) is a moonlighting protein involved in GDP-D-mannose biosynthesis and KAT1 potassium channel regulation. González-García A, et al. Plant Sci, 2024 Jan. PMID 37852415
    2. Arabidopsis phosphomannose isomerase 1, but not phosphomannose isomerase 2, is essential for ascorbic acid biosynthesis. Maruta T, et al. J Biol Chem, 2008 Oct 24. PMID 18755683, Free PMC Article
    3. Genetic and molecular identification of genes required for female gametophyte development and function in Arabidopsis. Pagnussat GC, et al. Development, 2005 Feb. PMID 15634699
    4. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
    5. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Maternal Embryo Effect Arrest 31 (MEE31) is a moonlighting protein involved in GDP-D-mannose biosynthesis and KAT1 potassium channel regulation.
      Title: Maternal Embryo Effect Arrest 31 (MEE31) is a moonlighting protein involved in GDP-D-mannose biosynthesis and KAT1 potassium channel regulation.
    2. phosphomannose isomerase 1, but not phosphomannose isomerase 2, is essential for ascorbic acid biosynthesis
      Title: Arabidopsis phosphomannose isomerase 1, but not phosphomannose isomerase 2, is essential for ascorbic acid biosynthesis.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_111125.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables mannose-6-phosphate isomerase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in GDP-mannose biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within embryo development ending in seed dormancy IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in response to L-ascorbic acid IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to cadmium ion IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to cobalt ion IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to light stimulus IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to zinc ion IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Mannose-6-phosphate isomerase, type I
    NP_186906.1
    • MATERNAL EFFECT EMBRYO ARREST 31 (MEE31); CONTAINS InterPro DOMAIN/s: Mannose-6-phosphate isomerase (InterPro:IPR016305), Cupin, RmlC-type (InterPro:IPR011051), Mannose-6-phosphate isomerase, type I (InterPro:IPR001250), RmlC-like jelly roll fold (InterPro:IPR014710), Phosphomannose isomerase, type I, conserved site (InterPro:IPR018050); BEST Arabidopsis thaliana protein match is: Mannose-6-phosphate isomerase, type I (TAIR:AT1G67070.1); Has 2386 Blast hits to 2370 proteins in 810 species: Archae - 2; Bacteria - 1207; Metazoa - 570; Fungi - 215; Plants - 91; Viruses - 0; Other Eukaryotes - 301 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      543346..545602 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_111125.4 → NP_186906.1  Mannose-6-phosphate isomerase, type I [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_186906.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9M884
      UniProtKB/TrEMBL
      A0A178VN24, A0A5S9X8J9
      Conserved Domains (1) summary
      PLN02288
      Location:25 → 411
      PLN02288; mannose-6-phosphate isomerase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9M884.1

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