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    RAP2.2 uncharacterized protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 820643, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RAP2.2
    Official Full Name
    uncharacterized protein
    Primary source
    TAIR:AT3G14230
    Locus tag
    AT3G14230
    See related
    Araport:AT3G14230
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    related to AP2 2
    Summary
    encodes a member of the ERF (ethylene response factor) subfamily B-2 of ERF/AP2 transcription factor family (RAP2.2). The protein contains one AP2 domain. There are 5 members in this subfamily including RAP2.2 AND RAP2.12.
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    Genomic context

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    See RAP2.2 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    3
    Sequence:
    Chromosome: 3; NC_003074.8 (4737120..4739298, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene GDSL-like lipase/acylhydrolase superfamily protein Neighboring gene GDSL-like Lipase/Acylhydrolase superfamily protein Neighboring gene GDSL-motif lipase 4 Neighboring gene Subtilase family protein Neighboring gene RING/U-box superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis RAP2.2 plays an important role in plant resistance to Botrytis cinerea and ethylene responses. Zhao Y, et al. New Phytol, 2012 Jul. PMID 22530619
    2. Arabidopsis RAP2.2: an ethylene response transcription factor that is important for hypoxia survival. Hinz M, et al. Plant Physiol, 2010 Jun. PMID 20357136, Free PMC Article
    3. Redundant ERF-VII Transcription Factors Bind to an Evolutionarily Conserved cis-Motif to Regulate Hypoxia-Responsive Gene Expression in Arabidopsis. Gasch P, et al. Plant Cell, 2016 Jan. PMID 26668304, Free PMC Article
    4. Hypoxia response protein HRM1 modulates the activity of mitochondrial electron transport chain in Arabidopsis under hypoxic stress. Tsai KJ, et al. New Phytol, 2023 Aug. PMID 37301985
    5. ETHYLENE RESPONSE FACTOR 74 (ERF74) plays an essential role in controlling a respiratory burst oxidase homolog D (RbohD)-dependent mechanism in response to different stresses in Arabidopsis. Yao Y, et al. New Phytol, 2017 Mar. PMID 28164334

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. ERF74 and ERF75 play a redundant role in the up-regulation of RbohD transcription and enhance the ROS burst during the early stages of the stress response. [ERF75]
      Title: ETHYLENE RESPONSE FACTOR 74 (ERF74) plays an essential role in controlling a respiratory burst oxidase homolog D (RbohD)-dependent mechanism in response to different stresses in Arabidopsis.
    2. An evolutionarily conserved 12-bp cis-regulatory motif that binds to and is sufficient for activation by RAP2.2 and RAP2.12 is identified.
      Title: Redundant ERF-VII Transcription Factors Bind to an Evolutionarily Conserved cis-Motif to Regulate Hypoxia-Responsive Gene Expression in Arabidopsis.
    3. RAP2.2, RAP2.3 and RAP2.12 play a role in modulating oxidative and osmotic stress tolerance during submergence acclimation.
      Title: The low oxygen, oxidative and osmotic stress responses synergistically act through the ethylene response factor VII genes RAP2.12, RAP2.2 and RAP2.3.
    4. RAP2.2 functions as an important regulator in Botrytis resistance and ethylene responses.
      Title: Arabidopsis RAP2.2 plays an important role in plant resistance to Botrytis cinerea and ethylene responses.
    5. Ethylene and RAP2.2, together with oxygen-dependent signal transduction, play an important role in the response to hypoxia.
      Title: Arabidopsis RAP2.2: an ethylene response transcription factor that is important for hypoxia survival.
    6. The action of SINAT2 may explain the recalcitrance of AtRAP2.2 protein levels to change by altering AtRAP2.2 transcription.
      Title: Transcription factor RAP2.2 and its interacting partner SINAT2: stable elements in the carotenogenesis of Arabidopsis leaves.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_112281.2
    NM_180251.3
    NM_180252.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables DNA binding TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables transcription cis-regulatory region binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within regulation of gene expression IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to hypoxia IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IC
    Inferred by Curator
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    NP_566482.1
    • related to AP2 2 (RAP2.2); CONTAINS InterPro DOMAIN/s: DNA-binding, integrase-type (InterPro:IPR016177), Pathogenesis-related transcriptional factor/ERF, DNA-binding (InterPro:IPR001471); BEST Arabidopsis thaliana protein match is: related to AP2 12 (TAIR:AT1G53910.2); Has 6244 Blast hits to 5852 proteins in 259 species: Archae - 0; Bacteria - 2; Metazoa - 0; Fungi - 0; Plants - 6195; Viruses - 4; Other Eukaryotes - 43 (source: NCBI BLink).
    NP_850582.1
    • related to AP2 2 (RAP2.2); CONTAINS InterPro DOMAIN/s: DNA-binding, integrase-type (InterPro:IPR016177), Pathogenesis-related transcriptional factor/ERF, DNA-binding (InterPro:IPR001471); BEST Arabidopsis thaliana protein match is: related to AP2 12 (TAIR:AT1G53910.2); Has 6242 Blast hits to 5845 proteins in 257 species: Archae - 0; Bacteria - 2; Metazoa - 0; Fungi - 2; Plants - 6193; Viruses - 4; Other Eukaryotes - 41 (source: NCBI BLink).
    NP_850583.1
    • related to AP2 2 (RAP2.2); CONTAINS InterPro DOMAIN/s: DNA-binding, integrase-type (InterPro:IPR016177), Pathogenesis-related transcriptional factor/ERF, DNA-binding (InterPro:IPR001471); BEST Arabidopsis thaliana protein match is: related to AP2 12 (TAIR:AT1G53910.2); Has 6242 Blast hits to 5847 proteins in 256 species: Archae - 0; Bacteria - 2; Metazoa - 0; Fungi - 0; Plants - 6195; Viruses - 4; Other Eukaryotes - 41 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      4737120..4739298 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_180251.3 → NP_850582.1  uncharacterized protein AT3G14230 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850582.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VM98, A0A5S9XC16, A0A654F726
      Conserved Domains (1) summary
      smart00380
      Location:123 → 186
      AP2; DNA-binding domain in plant proteins such as APETALA2 and EREBPs

    2. NM_180252.1 → NP_850583.1  uncharacterized protein AT3G14230 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850583.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VN40, A0A654F726, A0A7G2EI37
      Conserved Domains (1) summary
      smart00380
      Location:122 → 185
      AP2; DNA-binding domain in plant proteins such as APETALA2 and EREBPs

    3. NM_112281.2 → NP_566482.1  uncharacterized protein AT3G14230 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566482.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A8MRL7, O23104, Q8LE76, Q9LUM4
      UniProtKB/TrEMBL
      A0A178VM98, A0A654F726
      Conserved Domains (1) summary
      smart00380
      Location:127 → 190
      AP2; DNA-binding domain in plant proteins such as APETALA2 and EREBPs
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LUM4.2

    Gene LinkOut

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