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    KIN11 SNF1 kinase homolog 11 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 822566, updated on 18-Sep-2024

    Summary

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    Official Symbol
    KIN11
    Official Full Name
    SNF1 kinase homolog 11
    Primary source
    TAIR:AT3G29160
    Locus tag
    AT3G29160
    See related
    Araport:AT3G29160
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AKIN11; ATKIN11; SNF1 kinase homolog 11; SNF1-RELATED PROTEIN KINASE; SNF1-RELATED PROTEIN KINASE 1.2; SNRK1.2
    Summary
    encodes a SNF1-related protein kinase that physically interacts with SCF subunit SKP1/ASK1 and 20S proteosome subunit PAD1. It has also been shown to interact with the WD protein PDL1.
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    Genomic context

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    See KIN11 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    12
    Sequence:
    Chromosome: 3; NC_003074.8 (11128620..11132105, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene pseudo Neighboring gene transmembrane protein (DUF872) Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Impact of the SnRK1 protein kinase on sucrose homeostasis and the transcriptome during the diel cycle. Peixoto B, et al. Plant Physiol, 2021 Nov 3. PMID 34618060, Free PMC Article
    2. Arabidopsis SnRK1 negatively regulates phenylpropanoid metabolism via Kelch domain-containing F-box proteins. Wang B, et al. New Phytol, 2021 Mar. PMID 33253431
    3. The SnRK1 Kinase as Central Mediator of Energy Signaling between Different Organelles. Wurzinger B, et al. Plant Physiol, 2018 Feb. PMID 29311271, Free PMC Article
    4. SRK2C, a SNF1-related protein kinase 2, improves drought tolerance by controlling stress-responsive gene expression in Arabidopsis thaliana. Umezawa T, et al. Proc Natl Acad Sci U S A, 2004 Dec 7. PMID 15561775, Free PMC Article
    5. The evolutionarily conserved kinase SnRK1 orchestrates resource mobilization during Arabidopsis seedling establishment. Henninger M, et al. Plant Cell, 2022 Jan 20. PMID 34755865, Free PMC Article

    See all (41) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. TOR and SnRK1 fine tune SPEECHLESS transcription and protein stability to optimize stomatal development in response to exogenously supplied sugar.
      Title: TOR and SnRK1 fine tune SPEECHLESS transcription and protein stability to optimize stomatal development in response to exogenously supplied sugar.
    2. Impact of the SnRK1 protein kinase on sucrose homeostasis and the transcriptome during the diel cycle.
      Title: Impact of the SnRK1 protein kinase on sucrose homeostasis and the transcriptome during the diel cycle.
    3. The evolutionarily conserved kinase SnRK1 orchestrates resource mobilization during Arabidopsis seedling establishment.
      Title: The evolutionarily conserved kinase SnRK1 orchestrates resource mobilization during Arabidopsis seedling establishment.
    4. Arabidopsis SnRK1 negatively regulates phenylpropanoid metabolism via Kelch domain-containing F-box proteins.
      Title: Arabidopsis SnRK1 negatively regulates phenylpropanoid metabolism via Kelch domain-containing F-box proteins.
    5. Studies indicate that protein-serine-threonine kinase SnRK1 affects metabolic adaptation, including plastidial and mitochondrial functions [Review].
      Title: The SnRK1 Kinase as Central Mediator of Energy Signaling between Different Organelles.
    6. SNRK1.2 (At3g29160) role in regulating metabolism and transcription in response to cellular energy status.
      Title: The Energy-Signaling Hub SnRK1 Is Important for Sucrose-Induced Hypocotyl Elongation.
    7. FUS3 phosphorylation and SnRK1 are required for embryogenesis and integration of environmental cues to ensure the survival of the progeny.
      Title: SnRK1 phosphorylation of FUSCA3 positively regulates embryogenesis, seed yield, and plant growth at high temperature in Arabidopsis.
    8. Transcription activation function of AC2 and the inactivation of SnRK1.2 induced the transcriptome changes in Arabidopsis.
      Title: Altered expression of Arabidopsis genes in response to a multifunctional geminivirus pathogenicity protein.
    9. SnRK1 activities critically influence stress-inducible gene expression and the induction of stress tolerance. [SNRK1.2]
      Title: Regulatory functions of SnRK1 in stress-responsive gene expression and in plant growth and development.
    10. SnR2.8 might be involved in a parallel pathway for activation of AREB/ABF bZIP-type transcription factors in response to drought stress.
      Title: Two closely related subclass II SnRK2 protein kinases cooperatively regulate drought-inducible gene expression.
    Submit: New GeneRIF Correction See all GeneRIFs (13)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_113839.4
    NM_202645.3
    NM_202646.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables kinase binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within protein autophosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within protein phosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in response to trehalose IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    SNF1 kinase homolog 11
    NP_566843.1
    • SNF1 kinase homolog 11 (KIN11); FUNCTIONS IN: protein binding, protein kinase activity; INVOLVED IN: protein amino acid phosphorylation, protein amino acid autophosphorylation; LOCATED IN: cellular_component unknown; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Ubiquitin-associated/translation elongation factor EF1B, N-terminal (InterPro:IPR000449), Protein kinase, ATP binding site (InterPro:IPR017441), Kinase-associated KA1 (InterPro:IPR001772), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote (InterPro:IPR015940), Protein kinase, Snf1-like AMPK (InterPro:IPR015741), Protein kinase, catalytic domain (InterPro:IPR000719), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635), Calcium/calmodulin-dependent protein kinase-like (InterPro:IPR020636); BEST Arabidopsis thaliana protein match is: SNF1 kinase homolog 10 (TAIR:AT3G01090.2); Has 132401 Blast hits to 130141 proteins in 4718 species: Archae - 168; Bacteria - 14985; Metazoa - 49281; Fungi - 13291; Plants - 32075; Viruses - 530; Other Eukaryotes - 22071 (source: NCBI BLink).
    NP_974374.1
    • SNF1 kinase homolog 11 (KIN11); FUNCTIONS IN: protein binding, protein kinase activity; INVOLVED IN: protein amino acid phosphorylation, protein amino acid autophosphorylation; LOCATED IN: cellular_component unknown; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Ubiquitin-associated/translation elongation factor EF1B, N-terminal (InterPro:IPR000449), Protein kinase, ATP binding site (InterPro:IPR017441), Kinase-associated KA1 (InterPro:IPR001772), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase-like domain (InterPro:IPR011009), Protein kinase, Snf1-like AMPK (InterPro:IPR015741), Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote (InterPro:IPR015940), Protein kinase, catalytic domain (InterPro:IPR000719), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635), Calcium/calmodulin-dependent protein kinase-like (InterPro:IPR020636); BEST Arabidopsis thaliana protein match is: SNF1 kinase homolog 10 (TAIR:AT3G01090.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_974375.1
    • SNF1 kinase homolog 11 (KIN11); FUNCTIONS IN: protein binding, protein kinase activity; INVOLVED IN: protein amino acid phosphorylation, protein amino acid autophosphorylation; LOCATED IN: cellular_component unknown; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Ubiquitin-associated/translation elongation factor EF1B, N-terminal (InterPro:IPR000449), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote (InterPro:IPR015940), Protein kinase, Snf1-like AMPK (InterPro:IPR015741), Protein kinase, catalytic domain (InterPro:IPR000719), Calcium/calmodulin-dependent protein kinase-like (InterPro:IPR020636); BEST Arabidopsis thaliana protein match is: SNF1 kinase homolog 10 (TAIR:AT3G01090.3); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      11128620..11132105 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_202645.3 → NP_974374.1  SNF1 kinase homolog 11 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_974374.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A6XGQ9, P92958, P92968, Q3E7R4
      UniProtKB/TrEMBL
      A0A178V9G9, A0A5S9XH57, B9DGQ3
      Conserved Domains (3) summary
      cd12122
      Location:391 → 509
      AMPKA_C; C-terminal regulatory domain of 5'-AMP-activated protein kinase (AMPK) alpha catalytic subunit
      cd14335
      Location:294 → 334
      UBA_SnRK1_plant; UBA domain found in the plant sucrose nonfermenting-1-related kinase (SnRK1) proteins
      cd14079
      Location:17 → 272
      STKc_AMPK_alpha; Catalytic domain of the Alpha subunit of the Serine/Threonine Kinase, AMP-activated protein kinase

    2. NM_113839.4 → NP_566843.1  SNF1 kinase homolog 11 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566843.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A6XGQ9, P92958, P92968, Q3E7R4
      UniProtKB/TrEMBL
      A0A178V9G9, A0A5S9XH57, B9DGQ3
      Conserved Domains (3) summary
      cd12122
      Location:391 → 509
      AMPKA_C; C-terminal regulatory domain of 5'-AMP-activated protein kinase (AMPK) alpha catalytic subunit
      cd14335
      Location:294 → 334
      UBA_SnRK1_plant; UBA domain found in the plant sucrose nonfermenting-1-related kinase (SnRK1) proteins
      cd14079
      Location:17 → 272
      STKc_AMPK_alpha; Catalytic domain of the Alpha subunit of the Serine/Threonine Kinase, AMP-activated protein kinase

    3. NM_202646.1 → NP_974375.1  SNF1 kinase homolog 11 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_974375.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P92958
      Conserved Domains (3) summary
      smart00220
      Location:20 → 272
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14335
      Location:294 → 334
      UBA_SnRK1_plant; UBA domain found in the plant sucrose nonfermenting-1-related kinase (SnRK1) proteins
      cd14079
      Location:17 → 272
      STKc_AMPK_alpha; Catalytic domain of the Alpha subunit of the Serine/Threonine Kinase, AMP-activated protein kinase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P92958.1

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