NUDX13 nudix hydrolase homolog 13 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: NUDX13
Official Full Name: nudix hydrolase homolog 13
Primary source: TAIR:AT3G26690
Locus tag: AT3G26690
See related: Araport:AT3G26690
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ARABIDOPSIS THALIANA NUDIX HYDROLASE HOMOLOG 13; ATNUDT13; ATNUDX13; nudix hydrolase homolog 13
Summary: Encodes AtNUDT13, a mitochondrial Nudix hydrolase specific for long-chain diadenosine polyphosphates.
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Genomic context

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See NUDX13 in Genome Data Viewer

Location:: chromosome: 3

Exon count:: 6

Sequence:: Chromosome: 3; NC_003074.8 (9804253..9805781, complement)

Chromosome 3 - NC_003074.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

NUDT13 protein is targeted to the mitochondria; this is the first description of a plant pyrophosphatase catalyzing the hydrolysis of long-chain diadenosine polyphosphates, molecules with multiple biological activities
Title: Cloning and characterization of AtNUDT13, a novel mitochondrial Arabidopsis thaliana Nudix hydrolase specific for long-chain diadenosine polyphosphates.

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General gene information

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Homology

Orthologs from OrthoDB

NM_113580.2

Supported by ESTs:

NM_180305.2

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables bis(5'-adenosyl)-pentaphosphatase activity	IDA Inferred from Direct Assay more info	PubMed
enables hydrolase activity	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	ISM Inferred from Sequence Model more info
located_in mitochondrion	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: nudix hydrolase homolog 13

NP_189303.1

nudix hydrolase homolog 13 (NUDX13); CONTAINS InterPro DOMAIN/s: NUDIX hydrolase domain-like (InterPro:IPR015797), NUDIX hydrolase, conserved site (InterPro:IPR020084), NUDIX hydrolase domain (InterPro:IPR000086); BEST Arabidopsis thaliana protein match is: nudix hydrolase homolog 12 (TAIR:AT1G12880.1); Has 1216 Blast hits to 1215 proteins in 350 species: Archae - 0; Bacteria - 513; Metazoa - 242; Fungi - 111; Plants - 235; Viruses - 0; Other Eukaryotes - 115 (source: NCBI BLink).

NP_850636.1

nudix hydrolase homolog 13 (NUDX13); CONTAINS InterPro DOMAIN/s: NUDIX hydrolase domain-like (InterPro:IPR015797), NUDIX hydrolase, conserved site (InterPro:IPR020084), NUDIX hydrolase domain (InterPro:IPR000086); BEST Arabidopsis thaliana protein match is: nudix hydrolase homolog 12 (TAIR:AT1G12880.1); Has 1216 Blast hits to 1215 proteins in 350 species: Archae - 0; Bacteria - 513; Metazoa - 242; Fungi - 111; Plants - 235; Viruses - 0; Other Eukaryotes - 115 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003074.8 Reference assembly

Range

9804253..9805781 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_113580.2 → NP_189303.1 nudix hydrolase homolog 13 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_189303.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q29PY9, Q52K88

UniProtKB/TrEMBL

A0A178VBM7, A0A5S9XGB5

Conserved Domains (1) summary

cd04666
Location:21 → 160

Nudix_Hydrolase_9; Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly ...
NM_180305.2 → NP_850636.1 nudix hydrolase homolog 13 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_850636.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q29PY9, Q52K88

UniProtKB/TrEMBL

A0A178VBM7, A0A5S9XGB5

Conserved Domains (1) summary

cd04666
Location:21 → 160

Nudix_Hydrolase_9; Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly ...