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    CYN cyanase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 821930, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CYN
    Official Full Name
    cyanase
    Primary source
    TAIR:AT3G23490
    Locus tag
    AT3G23490
    See related
    Araport:AT3G23490
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    cyanase; CYANASE
    Summary
    Encodes a cyanase that catalyzes the bicarbonate-dependent breakdown of cyanate to ammonia and bicarbonate. CYN forms a hexadecamer and is believed to be a cytosolic protein. Long-term exposure to NaCl increases CYN transcript levels. It is also expressed at higher levels in flowers relative to stems, roots, and seedlings.
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    Genomic context

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    See CYN in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    5
    Sequence:
    Chromosome: 3; NC_003074.8 (8422649..8424652, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene S-adenosyl-L-methionine-dependent methyltransferases superfamily protein Neighboring gene Cyclopropane-fatty-acyl-phospholipid synthase Neighboring gene Cyclopropane-fatty-acyl-phospholipid synthase Neighboring gene ncRNA Neighboring gene Cyclopropane-fatty-acyl-phospholipid synthase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Biochemical and structural properties of cyanases from Arabidopsis thaliana and Oryza sativa. Qian D, et al. PLoS One, 2011 Mar 31. PMID 21494323, Free PMC Article
    2. A proteomic strategy for global analysis of plant protein complexes. Aryal UK, et al. Plant Cell, 2014 Oct. PMID 25293756, Free PMC Article
    3. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article
    4. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001338644.1
    NM_113252.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables cyanate hydratase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables cyanate hydratase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cyanate catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in cyanate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within response to salt stress IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytosol HDA PubMed 

    General protein information

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    Preferred Names
    cyanase
    NP_188991.1
    • cyanase (CYN); FUNCTIONS IN: hydro-lyase activity, DNA binding, cyanate hydratase activity; INVOLVED IN: cyanate metabolic process, metabolic process; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Lambda repressor-like, DNA-binding (InterPro:IPR010982), Cyanase (InterPro:IPR008076), Cyanate lyase, C-terminal (InterPro:IPR003712); Has 993 Blast hits to 992 proteins in 414 species: Archae - 3; Bacteria - 787; Metazoa - 7; Fungi - 73; Plants - 52; Viruses - 0; Other Eukaryotes - 71 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      8422649..8424652 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001338643.1 → NP_001327887.1  cyanase [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O22683
      UniProtKB/TrEMBL
      A0A178VD28, A0A5S9XEX0, Q8LDF0
      Conserved Domains (1) summary
      PRK02866
      Location:5 → 146
      PRK02866; cyanate hydratase; Validated

    2. NM_113252.4 → NP_188991.1  cyanase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_188991.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O22683
      UniProtKB/TrEMBL
      A0A178VD28, A0A5S9XEX0, Q8LDF0
      Conserved Domains (1) summary
      PRK02866
      Location:5 → 146
      PRK02866; cyanate hydratase; Validated

    3. NM_001338644.1 → NP_001327888.1  cyanase [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LTP8
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O22683.1

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