U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    PUX1 plant UBX domain-containing protein 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 822350, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    PUX1
    Official Full Name
    plant UBX domain-containing protein 1
    Primary source
    TAIR:AT3G27310
    Locus tag
    AT3G27310
    See related
    Araport:AT3G27310
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    K17E12.13; plant UBX domain-containing protein 1
    Summary
    encodes a protein that contains a UBX domain and regulates AtCDC48 by inhibiting its ATPase activity and by promoting the disassembly of the active hexamer. Phenotypic analysis of pux1 plants revealed that the loss of PUX1 accelerated the growth of various plant organs including roots and inflorescence shoots. AtCDC48 and SYP31 colocalize at the division plane during cytokinesis and to interact in vitro and in vivo.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See PUX1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    7
    Sequence:
    Chromosome: 3; NC_003074.8 (10087106..10089260, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene RNI-like superfamily protein Neighboring gene glucose-6-phosphate dehydrogenase 5 Neighboring gene alpha/beta-Hydrolases superfamily protein Neighboring gene miscRNA

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Plant UBX domain-containing protein 1, PUX1, regulates the oligomeric structure and activity of arabidopsis CDC48. Rancour DM, et al. J Biol Chem, 2004 Dec 24. PMID 15498773
    2. Common Mode of Remodeling AAA ATPases p97/CDC48 by Their Disassembling Cofactors ASPL/PUX1. Banchenko S, et al. Structure, 2019 Dec 3. PMID 31648844
    3. Protein domain-domain interactions and requirements for the negative regulation of Arabidopsis CDC48/p97 by the plant ubiquitin regulatory X (UBX) domain-containing protein, PUX1. Park S, et al. J Biol Chem, 2007 Feb 23. PMID 17190830
    4. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help
    NM_113645.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATPase binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within organ growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within protein-containing complex disassembly IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in protein-containing complex disassembly IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    plant UBX domain-containing protein 1
    NP_566815.1
    • plant UBX domain-containing protein 1 (PUX1); CONTAINS InterPro DOMAIN/s: UBX (InterPro:IPR001012); Has 392 Blast hits to 391 proteins in 121 species: Archae - 0; Bacteria - 0; Metazoa - 209; Fungi - 47; Plants - 86; Viruses - 0; Other Eukaryotes - 50 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      10087106..10089260 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_113645.3 → NP_566815.1  plant UBX domain-containing protein 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566815.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LK22
      UniProtKB/TrEMBL
      A0A5S9XGJ9, A0A654FGK0
      Conserved Domains (1) summary
      cd16118
      Location:109 → 181
      UBX2_UBXN9; Ubiquitin regulatory domain X (UBX) 2 found in UBX domain protein 9 (UBXN9, UBXD9, or ASPSCR1) and similar proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LK22.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools