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    NUC-L2 nucleolin like 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 821392, updated on 18-Sep-2024

    Summary

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    Official Symbol
    NUC-L2
    Official Full Name
    nucleolin like 2
    Primary source
    TAIR:AT3G18610
    Locus tag
    AT3G18610
    See related
    Araport:AT3G18610
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATNUC-L2; ATRANGAP1; NUC2; nucleolin 2; nucleolin like 2; PARALLEL1-LIKE 1; PARLL1; RAN GTPASE-ACTIVATING PROTEIN 1
    Summary
    Encodes ATNUC-L2 (NUCLEOLIN LIKE 2).
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    Genomic context

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    See NUC-L2 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    18
    Sequence:
    Chromosome: 3; NC_003074.8 (6404053..6407946, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene early nodulin-like protein 5 Neighboring gene P-loop containing nucleoside triphosphate hydrolases superfamily protein Neighboring gene DHHC-type zinc finger family protein Neighboring gene uracil dna glycosylase Neighboring gene Zinc finger C-x8-C-x5-C-x3-H type family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A duplicated NUCLEOLIN gene with antagonistic activity is required for chromatin organization of silent 45S rDNA in Arabidopsis. Durut N, et al. Plant Cell, 2014 Mar. PMID 24668745, Free PMC Article
    2. Characterization of AtNUC-L1 reveals a central role of nucleolin in nucleolus organization and silencing of AtNUC-L2 gene in Arabidopsis. Pontvianne F, et al. Mol Biol Cell, 2007 Feb. PMID 17108323, Free PMC Article
    3. Dual Role of a SAS10/C1D Family Protein in Ribosomal RNA Gene Expression and Processing Is Essential for Reproduction in Arabidopsis thaliana. Chen YC, et al. PLoS Genet, 2016 Oct. PMID 27792779, Free PMC Article
    4. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_112747.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables nucleosome binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within rDNA heterochromatin formation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleolus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    nucleolin like 2
    NP_188491.1
    • nucleolin like 2 (NUC-L2); FUNCTIONS IN: nucleotide binding, nucleic acid binding; EXPRESSED IN: egg cell, cultured cell; CONTAINS InterPro DOMAIN/s: RNA recognition motif, RNP-1 (InterPro:IPR000504), Nucleotide-binding, alpha-beta plait (InterPro:IPR012677); BEST Arabidopsis thaliana protein match is: nucleolin like 1 (TAIR:AT1G48920.1); Has 220619 Blast hits to 110675 proteins in 3421 species: Archae - 647; Bacteria - 30556; Metazoa - 92066; Fungi - 36057; Plants - 14337; Viruses - 1241; Other Eukaryotes - 45715 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      6404053..6407946 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001338347.1 → NP_001325664.1  nucleolin like 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VLH5, A0A1I9LLX8

    2. NM_001338348.1 → NP_001325663.1  nucleolin like 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LLX7, A0A5S9XDS0

    3. NM_112747.3 → NP_188491.1  nucleolin like 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_188491.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q1PEP5, Q9LIH8
      UniProtKB/TrEMBL
      A0A5S9XDS0, A0A654F8H7
      Conserved Domains (2) summary
      cd12450
      Location:385 → 461
      RRM1_NUCLs; RNA recognition motif 1 (RRM1) found in nucleolin-like proteins mainly from plants
      cd12451
      Location:480 → 556
      RRM2_NUCLs; RNA recognition motif 2 (RRM2) found in nucleolin-like proteins mainly from plants
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q1PEP5.1

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