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    TRAF-like superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 820573, updated on 18-Sep-2024

    Summary

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    Official Full Name
    TRAF-like superfamily protein
    Primary source
    TAIR:AT3G13672
    Locus tag
    AT3G13672
    See related
    Araport:AT3G13672
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    SINA2
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    Genomic context

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    Location:
    chromosome: 3
    Exon count:
    3
    Sequence:
    Chromosome: 3; NC_003074.8 (4472562..4474378, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Disease resistance-responsive (dirigent-like protein) family protein Neighboring gene Disease resistance-responsive (dirigent-like protein) family protein Neighboring gene Protein kinase family protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene F-box and associated interaction domains-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Phosphorylation of Arabidopsis SINA2 by CDKG1 affects its ubiquitin ligase activity. Chen Y, et al. BMC Plant Biol, 2018 Jul 16. PMID 30012094, Free PMC Article
    2. The tumor necrosis factor receptor-associated factor (TRAF)-like family protein SEVEN IN ABSENTIA 2 (SINA2) promotes drought tolerance in an ABA-dependent manner in Arabidopsis. Bao Y, et al. New Phytol, 2014 Apr. PMID 24350984
    3. TRAF Family Proteins Regulate Autophagy Dynamics by Modulating AUTOPHAGY PROTEIN6 Stability in Arabidopsis. Qi H, et al. Plant Cell, 2017 Apr. PMID 28351989, Free PMC Article
    4. Extensive signal integration by the phytohormone protein network. Altmann M, et al. Nature, 2020 Jul. PMID 32612234
    5. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. phosphorylation by CDKG1 affects its ubiquitin ligase activity to regulate its effect on responses to ABA and osmotic stress
      Title: Phosphorylation of Arabidopsis SINA2 by CDKG1 affects its ubiquitin ligase activity.
    2. SINA2 functions as a positive molecular link between drought tolerance and abscissic acid signaling in Arabidopsis.[SINA2]
      Title: The tumor necrosis factor receptor-associated factor (TRAF)-like family protein SEVEN IN ABSENTIA 2 (SINA2) promotes drought tolerance in an ABA-dependent manner in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001338064.1
    NM_112215.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein homodimerization activity IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of response to water deprivation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein ubiquitination IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in regulation of autophagosome assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    TRAF-like superfamily protein
    NP_001319542.1
    • TRAF-like superfamily protein; FUNCTIONS IN: molecular_function unknown; INVOLVED IN: multicellular organismal development, ubiquitin-dependent protein catabolic process; LOCATED IN: nucleus; EXPRESSED IN: 11 plant structures; EXPRESSED DURING: LP.06 six leaves visible, LP.04 four leaves visible, 4 anthesis, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: TRAF-like (InterPro:IPR008974), Seven-in-absentia protein, TRAF-like domain (InterPro:IPR018121), Seven-in-absentia protein, sina (InterPro:IPR004162), TRAF-type (InterPro:IPR013322); BEST Arabidopsis thaliana protein match is: seven in absentia of Arabidopsis 2 (TAIR:AT3G58040.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_187978.1
    • TRAF-like superfamily protein; FUNCTIONS IN: molecular_function unknown; INVOLVED IN: multicellular organismal development, ubiquitin-dependent protein catabolic process; LOCATED IN: nucleus; EXPRESSED IN: 11 plant structures; EXPRESSED DURING: LP.06 six leaves visible, LP.04 four leaves visible, 4 anthesis, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: TRAF-like (InterPro:IPR008974), Seven-in-absentia protein, TRAF-like domain (InterPro:IPR018121), Seven-in-absentia protein, sina (InterPro:IPR004162), TRAF-type (InterPro:IPR013322); BEST Arabidopsis thaliana protein match is: seven in absentia of Arabidopsis 2 (TAIR:AT3G58040.1); Has 478 Blast hits to 478 proteins in 76 species: Archae - 0; Bacteria - 0; Metazoa - 245; Fungi - 0; Plants - 224; Viruses - 0; Other Eukaryotes - 9 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      4472562..4474378 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_112215.2 → NP_187978.1  TRAF-like superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_187978.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q93WE4, Q9LID2
      UniProtKB/TrEMBL
      A0A178V5T3, A0A5S9XC63
      Conserved Domains (1) summary
      pfam03145
      Location:5 → 205
      Sina; Seven in absentia protein family

    2. NM_001338064.1 → NP_001319542.1  TRAF-like superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4JDF6
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q93WE4.1

    Gene LinkOut

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