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    ATBFRUCT1 Glycosyl hydrolases family 32 protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 820591, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ATBFRUCT1
    Official Full Name
    Glycosyl hydrolases family 32 protein
    Primary source
    TAIR:AT3G13790
    Locus tag
    AT3G13790
    See related
    Araport:AT3G13790
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA CELL WALL INVERTASE 1; ATCWINV1
    Summary
    Encodes a protein with invertase activity.
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    Genomic context

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    See ATBFRUCT1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    6
    Sequence:
    Chromosome: 3; NC_003074.8 (4532762..4535914, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene nucleosome assembly protein1;4 Neighboring gene cell wall invertase 5 Neighboring gene ncRNA Neighboring gene Metallo-hydrolase/oxidoreductase superfamily protein Neighboring gene ncRNA Neighboring gene indeterminate(ID)-domain 11

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Targeting the AtCWIN1 Gene to Explore the Role of Invertases in Sucrose Transport in Roots and during Botrytis cinerea Infection. Veillet F, et al. Front Plant Sci, 2016. PMID 28066461, Free PMC Article
    2. Crystal structures of Arabidopsis thaliana cell-wall invertase mutants in complex with sucrose. Lammens W, et al. J Mol Biol, 2008 Mar 21. PMID 18258263
    3. An alternate sucrose binding mode in the E203Q Arabidopsis invertase mutant: an X-ray crystallography and docking study. Mátrai J, et al. Proteins, 2008 May 1. PMID 17963237
    4. Unraveling the difference between invertases and fructan exohydrolases: a single amino acid (Asp-239) substitution transforms Arabidopsis cell wall invertase1 into a fructan 1-exohydrolase. Le Roy K, et al. Plant Physiol, 2007 Nov. PMID 17873089, Free PMC Article
    5. X-ray diffraction structure of a cell-wall invertase from Arabidopsis thaliana. Verhaest M, et al. Acta Crystallogr D Biol Crystallogr, 2006 Dec. PMID 17139091

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. E203Q mutation introduced into the catalytic pocket triggers conformational changes that alter the wild type substrate binding.
      Title: An alternate sucrose binding mode in the E203Q Arabidopsis invertase mutant: an X-ray crystallography and docking study.
    2. report on different X-ray crystal structures of Arabidopsis thaliana cell-wall invertase 1 (AtcwINV1) mutants with sucrose
      Title: Crystal structures of Arabidopsis thaliana cell-wall invertase mutants in complex with sucrose.
    3. This study showed that a D239A mutant of INV1 acted as a 1-fructan exohydrolase, preferentially degrading 1-kestose.
      Title: Unraveling the difference between invertases and fructan exohydrolases: a single amino acid (Asp-239) substitution transforms Arabidopsis cell wall invertase1 into a fructan 1-exohydrolase.
    4. The structure of the Arabidopsis thaliana cell-wall invertase 1 (AtcwINV1; gene accession code At3g13790) is described at a resolution of 2.15 A.
      Title: X-ray diffraction structure of a cell-wall invertase from Arabidopsis thaliana.
    5. Enzyme activity measurements, quantitative RT-PCR, and T-DNA insertional mutagenesis have been used to determine that expression of AtcwINV1 is responsible for all induced cwINV activity in mechanically wounded leaves
      Title: Imaging photosynthesis in wounded leaves of Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001202952.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables beta-fructofuranosidase activity IDA
    Inferred from Direct Assay
    more info
    		  
    enables beta-fructofuranosidase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables hydrolase activity, hydrolyzing O-glycosyl compounds IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within defense response to fungus IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to wounding IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasmic stress granule IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plant-type cell wall HDA PubMed 
    located_in plasma membrane HDA PubMed 

    General protein information

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    Preferred Names
    Glycosyl hydrolases family 32 protein
    NP_001189881.1
    • ATBFRUCT1; CONTAINS InterPro DOMAIN/s: Glycoside hydrolase, family 32 (InterPro:IPR001362), Glycosyl hydrolases family 32, N-terminal (InterPro:IPR013148), Glycosyl hydrolase family 32, C-terminal (InterPro:IPR013189), Concanavalin A-like lectin/glucanase (InterPro:IPR008985); BEST Arabidopsis thaliana protein match is: beta-fructofuranosidase 5 (TAIR:AT1G55120.1).
    NP_566464.1
    • ATBFRUCT1; FUNCTIONS IN: hydrolase activity, hydrolyzing O-glycosyl compounds, beta-fructofuranosidase activity; INVOLVED IN: response to karrikin, response to wounding; LOCATED IN: cell wall; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Glycoside hydrolase, family 32 (InterPro:IPR001362), Glycoside hydrolase, family 32, active site (InterPro:IPR018053), Glycosyl hydrolases family 32, N-terminal (InterPro:IPR013148), Glycosyl hydrolase family 32, C-terminal (InterPro:IPR013189), Concanavalin A-like lectin/glucanase (InterPro:IPR008985); BEST Arabidopsis thaliana protein match is: beta-fructofuranosidase 5 (TAIR:AT1G55120.1); Has 4230 Blast hits to 4174 proteins in 1237 species: Archae - 18; Bacteria - 2583; Metazoa - 93; Fungi - 290; Plants - 1044; Viruses - 0; Other Eukaryotes - 202 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      4532762..4535914 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_112232.4 → NP_566464.1  Glycosyl hydrolases family 32 protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566464.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q43866, Q9LIB8
      UniProtKB/TrEMBL
      A0A5S9XBW4, A0A654F8K5
      Conserved Domains (1) summary
      smart00640
      Location:56 → 538
      Glyco_32; Glycosyl hydrolases family 32

    2. NM_001338080.1 → NP_001327314.1  Glycosyl hydrolases family 32 protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VMK1, A0A1I9LRX7, A0A7G2EKG3
      Conserved Domains (1) summary
      smart00640
      Location:1 → 468
      Glyco_32; Glycosyl hydrolases family 32

    3. NM_001338079.1 → NP_001327313.1  Glycosyl hydrolases family 32 protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VMK1, A0A1I9LRX7, A0A7G2EKG3
      Conserved Domains (1) summary
      smart00640
      Location:1 → 468
      Glyco_32; Glycosyl hydrolases family 32

    4. NM_001338081.1 → NP_001327315.1  Glycosyl hydrolases family 32 protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VMK1, A0A1I9LRX7, A0A7G2EKG3
      Conserved Domains (1) summary
      smart00640
      Location:1 → 468
      Glyco_32; Glycosyl hydrolases family 32

    5. NM_001202952.1 → NP_001189881.1  Glycosyl hydrolases family 32 protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001189881.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A654F8K5, F4JEJ0
      Conserved Domains (3) summary
      smart00640
      Location:56 → 535
      Glyco_32; Glycosyl hydrolases family 32
      pfam00251
      Location:56 → 375
      Glyco_hydro_32N; Glycosyl hydrolases family 32 N-terminal domain
      pfam08244
      Location:448 → 535
      Glyco_hydro_32C; Glycosyl hydrolases family 32 C terminal
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q43866.1

    Gene LinkOut

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