U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    MBD8 methyl-CPG-binding domain 8 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838838, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    MBD8
    Official Full Name
    methyl-CPG-binding domain 8
    Primary source
    TAIR:AT1G22310
    Locus tag
    AT1G22310
    See related
    Araport:AT1G22310
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATMBD8; methyl-CPG-binding domain 8; T16E15.7; T16E15_7
    Summary
    Protein containing methyl-CpG-binding domain.Has sequence similarity to human MBD proteins.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See MBD8 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    2
    Sequence:
    Chromosome: 1; NC_003070.9 (7881503..7883824, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene 14-3-3 family protein Neighboring gene general regulatory factor 10 Neighboring gene tRNA-Met Neighboring gene RNA-binding (RRM/RBD/RNP motifs) family protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. AtMBD8 is involved in control of flowering time in the C24 ecotype of Arabidopsis thaliana. Stangeland B, et al. Physiol Plant, 2009 May. PMID 19374717
    2. Methylated DNA-binding proteins from Arabidopsis. Ito M, et al. Plant Physiol, 2003 Dec. PMID 14605234, Free PMC Article
    3. Characterization of Arabidopsis thaliana methyl-CpG-binding domain (MBD) proteins. Zemach A, et al. Plant J, 2003 Jun. PMID 12787239
    4. CrY2H-seq: a massively multiplexed assay for deep-coverage interactome mapping. Wanamaker SA, et al. Nat Methods, 2017 Aug. PMID 28650476, Free PMC Article
    5. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. AtMBD8 is a novel promoter of flowering that acts upstream of FT in the C24 accession.
      Title: AtMBD8 is involved in control of flowering time in the C24 ecotype of Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    NM_102082.4
    NM_180618.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables methyl-CpG binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    methyl-CPG-binding domain 8
    NP_173650.3
    • methyl-CPG-binding domain 8 (MBD8); FUNCTIONS IN: methyl-CpG binding; INVOLVED IN: biological_process unknown; LOCATED IN: nucleus; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: AT hook, DNA-binding motif (InterPro:IPR017956), DNA-binding, integrase-type (InterPro:IPR016177), Methyl-CpG DNA binding (InterPro:IPR001739); Has 148 Blast hits to 124 proteins in 33 species: Archae - 0; Bacteria - 2; Metazoa - 54; Fungi - 5; Plants - 70; Viruses - 0; Other Eukaryotes - 17 (source: NCBI BLink).
    NP_850949.1
    • methyl-CPG-binding domain 8 (MBD8); FUNCTIONS IN: methyl-CpG binding; INVOLVED IN: biological_process unknown; LOCATED IN: nucleus; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: A.T hook-like (InterPro:IPR020478), AT hook, DNA-binding motif (InterPro:IPR017956), DNA-binding, integrase-type (InterPro:IPR016177), Methyl-CpG DNA binding (InterPro:IPR001739); Has 54 Blast hits to 54 proteins in 16 species: Archae - 0; Bacteria - 2; Metazoa - 3; Fungi - 0; Plants - 44; Viruses - 2; Other Eukaryotes - 3 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      7881503..7883824 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_102082.4 → NP_173650.3  methyl-CPG-binding domain 8 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_173650.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8RXV1, Q9LME6
      UniProtKB/TrEMBL
      A0A178WFY1, A0A5S9VM51, A0A654EH66
      Conserved Domains (1) summary
      cl00110
      Location:344 → 388
      MBD; MeCP2, MBD1, MBD2, MBD3, MBD4, CLLD8-like, and BAZ2A-like proteins constitute a family of proteins that share the methyl-CpG-binding domain (MBD). The MBD consists of about 70 residues and is defined as the minimal region required for binding to ...

    2. NM_180618.2 → NP_850949.1  methyl-CPG-binding domain 8 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850949.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LME6
      Conserved Domains (1) summary
      cl00110
      Location:245 → 289
      MBD; MeCP2, MBD1, MBD2, MBD3, MBD4, CLLD8-like, and BAZ2A-like proteins constitute a family of proteins that share the methyl-CpG-binding domain (MBD). The MBD consists of about 70 residues and is defined as the minimal region required for binding to ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LME6.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools