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    Vps51/Vps67 family (components of vesicular transport) protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 828155, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Vps51/Vps67 family (components of vesicular transport) protein
    Primary source
    TAIR:AT4G02030
    Locus tag
    AT4G02030
    See related
    Araport:AT4G02030
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T10M13.4; T10M13_4; UNH; UNHINGED; vacuolar protein sorting 51; VPS51
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    Genomic context

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    Location:
    chromosome: 4
    Exon count:
    22
    Sequence:
    Chromosome: 4; NC_003075.7 (892082..897359)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene Protein kinase superfamily protein Neighboring gene SET domain-containing protein Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene sugar transporter protein 7 Neighboring gene Minichromosome maintenance (MCM2/3/5) family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis UNHINGED encodes a VPS51 homolog and reveals a role for the GARP complex in leaf shape and vein patterning. Pahari S, et al. Development, 2014 May. PMID 24757006
    2. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article
    3. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. UNH is important for reducing expression of PIN1 within margin cells, possibly by targeting PIN1 to the lytic vacuole. [UNHINGED] [UNH]
      Title: Arabidopsis UNHINGED encodes a VPS51 homolog and reveals a role for the GARP complex in leaf shape and vein patterning.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001203725.1
    NM_116434.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in autophagy ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in endocytic recycling ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    NOT involved_in endocytosis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in leaf vascular tissue pattern formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in retrograde transport, endosome to Golgi ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in vacuolar transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in vesicle-mediated transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of EARP complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    part_of GARP complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in recycling endosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    colocalizes_with trans-Golgi network IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Vps51/Vps67 family (components of vesicular transport) protein
    NP_001190654.1
    • Vps51/Vps67 family (components of vesicular transport) protein; FUNCTIONS IN: molecular_function unknown; INVOLVED IN: biological_process unknown; LOCATED IN: cellular_component unknown; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Vps51/Vps67 (InterPro:IPR014812).
    NP_192112.2
    • Vps51/Vps67 family (components of vesicular transport) protein; CONTAINS InterPro DOMAIN/s: Vps51/Vps67 (InterPro:IPR014812); Has 511 Blast hits to 475 proteins in 172 species: Archae - 2; Bacteria - 9; Metazoa - 205; Fungi - 94; Plants - 90; Viruses - 4; Other Eukaryotes - 107 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      892082..897359
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_116434.4 → NP_192112.2  Vps51/Vps67 family (components of vesicular transport) protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_192112.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O04247, Q0WQ75
      UniProtKB/TrEMBL
      A0A5S9XPX7, A0A654FLD9
      Conserved Domains (2) summary
      pfam08700
      Location:43 → 128
      Vps51; Vps51/Vps67
      cl19297
      Location:83 → 255
      Dor1; Dor1-like family

    2. NM_001203725.1 → NP_001190654.1  Vps51/Vps67 family (components of vesicular transport) protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001190654.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9XPX7, F4JH69
      Conserved Domains (2) summary
      pfam08700
      Location:83 → 153
      Vps51; Vps51/Vps67
      cl19297
      Location:108 → 293
      Dor1; Dor1-like family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q0WQ75.1

    Gene LinkOut

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