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    GA1 Terpenoid cyclases/Protein prenyltransferases superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 828182, updated on 18-Sep-2024

    Summary

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    Official Symbol
    GA1
    Official Full Name
    Terpenoid cyclases/Protein prenyltransferases superfamily protein
    Primary source
    TAIR:AT4G02780
    Locus tag
    AT4G02780
    See related
    Araport:AT4G02780
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ABC33; ARABIDOPSIS THALIANA ENT-COPALYL DIPHOSPHATE SYNTHETASE 1; ATCPS1; CPP synthase; CPS; CPS1; ENT-COPALYL DIPHOSPHATE SYNTHETASE; ENT-COPALYL DIPHOSPHATE SYNTHETASE 1; GA REQUIRING 1; T5J8.9; T5J8_9
    Summary
    Catalyzes the conversion of geranylgeranyl pyrophosphate (GGPP) to copalyl pyrophosphate (CPP) of gibberellin biosynthesis
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    Genomic context

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    See GA1 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    15
    Sequence:
    Chromosome: 4; NC_003075.7 (1237671..1244822, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene RNI-like superfamily protein Neighboring gene photosystem I subunit D-1 Neighboring gene GTP-binding family protein Neighboring gene GRIP/coiled-coil protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Natural variation in GA1 associates with floral morphology in Arabidopsis thaliana. Brock MT, et al. New Phytol, 2012 Jul. PMID 22510148
    2. Synergistic substrate inhibition of ent-copalyl diphosphate synthase: a potential feed-forward inhibition mechanism limiting gibberellin metabolism. Prisic S, et al. Plant Physiol, 2007 May. PMID 17384166, Free PMC Article
    3. The Arabidopsis GA1 locus encodes the cyclase ent-kaurene synthetase A of gibberellin biosynthesis. Sun TP, et al. Plant Cell, 1994 Oct. PMID 7994182, Free PMC Article
    4. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    NM_116512.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ent-copalyl diphosphate synthase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables ent-copalyl diphosphate synthase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables magnesium ion binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables terpene synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within gibberellic acid mediated signaling pathway TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within gibberellin biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in gibberellin biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within gibberellin biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Terpenoid cyclases/Protein prenyltransferases superfamily protein
    NP_192187.1
    • GA REQUIRING 1 (GA1); CONTAINS InterPro DOMAIN/s: Terpene synthase, metal-binding domain (InterPro:IPR005630), Terpenoid synthase (InterPro:IPR008949), Terpenoid cylases/protein prenyltransferase alpha-alpha toroid (InterPro:IPR008930), Terpene synthase-like (InterPro:IPR001906); BEST Arabidopsis thaliana protein match is: Terpenoid cyclases/Protein prenyltransferases superfamily protein (TAIR:AT1G79460.1); Has 1979 Blast hits to 1971 proteins in 256 species: Archae - 0; Bacteria - 97; Metazoa - 0; Fungi - 61; Plants - 1817; Viruses - 0; Other Eukaryotes - 4 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      1237671..1244822 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_116512.2 → NP_192187.1  Terpenoid cyclases/Protein prenyltransferases superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_192187.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q38802
      UniProtKB/TrEMBL
      A0A654FLC6
      Conserved Domains (1) summary
      PLN02592
      Location:31 → 802
      PLN02592; ent-copalyl diphosphate synthase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q38802.1

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