CIPK12 CBL-interacting protein kinase 12 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: CIPK12
Official Full Name: CBL-interacting protein kinase 12
Primary source: TAIR:AT4G18700
Locus tag: AT4G18700
See related: Araport:AT4G18700
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ATWL4; CBL-interacting protein kinase 12; F28A21.110; F28A21_110; PKS8; protein kinase 8; SNF1-RELATED PROTEIN KINASE 3.9; SnRK3.9; WL4; WPL4-LIKE 4
Summary: Encodes CBL-interacting protein kinase 12 (CIPK12).
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Genomic context

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See CIPK12 in Genome Data Viewer

Location:: chromosome: 4

Exon count:: 1

Sequence:: Chromosome: 4; NC_003075.7 (10288798..10291058, complement)

Chromosome 4 - NC_003075.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

balanced activity of Ca(2+)-activated CBL2/3-CIPK12 complexes fulfills fundamental functions to enable the fast growth of pollen tubes in higher plants
Title: Vacuolar CBL-CIPK12 Ca(2+)-sensor-kinase complexes are required for polarized pollen tube growth.

Submit: New GeneRIF Correction

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_117986.3

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein serine/threonine kinase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in signal transduction	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in plasma membrane	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: CBL-interacting protein kinase 12

NP_193605.1

CBL-interacting protein kinase 12 (CIPK12); FUNCTIONS IN: protein serine/threonine kinase activity, protein kinase activity, kinase activity, ATP binding; INVOLVED IN: signal transduction, protein amino acid phosphorylation; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Serine/threonine-protein kinase domain (InterPro:IPR002290), NAF/FISL domain (InterPro:IPR018451), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271), NAF domain (InterPro:IPR004041), CBL-interacting protein kinase (InterPro:IPR020660), Protein kinase, catalytic domain (InterPro:IPR000719), Calcium/calmodulin-dependent protein kinase-like (InterPro:IPR020636); BEST Arabidopsis thaliana protein match is: CBL-interacting protein kinase 19 (TAIR:AT5G45810.1); Has 132740 Blast hits to 130588 proteins in 4556 species: Archae - 205; Bacteria - 15732; Metazoa - 48597; Fungi - 13262; Plants - 32355; Viruses - 523; Other Eukaryotes - 22066 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003075.7 Reference assembly

Range

10288798..10291058 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_117986.3 → NP_193605.1 CBL-interacting protein kinase 12 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_193605.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q9SN43

UniProtKB/TrEMBL

A0A178UZU5, A0A5S9XUK1

Conserved Domains (2) summary

cd12195
Location:342 → 453

CIPK_C; C-terminal regulatory domain of Calcineurin B-Like (CBL)-interacting protein kinases

cd14663
Location:25 → 279

STKc_SnRK3; Catalytic domain of the Serine/Threonine Kinases, Sucrose nonfermenting 1-related protein kinase subfamily 3