SHB1 EXS (ERD1/XPR1/SYG1) family protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: SHB1
Official Full Name: EXS (ERD1/XPR1/SYG1) family protein
Primary source: TAIR:AT4G25350
Locus tag: AT4G25350
See related: Araport:AT4G25350
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: SHORT HYPOCOTYL UNDER BLUE1; T30C3.10; T30C3_10
Summary: SHB1 encodes a nuclear and cytosolic protein that has motifs homologous with SYG1 protein family members. Acts in cryptochrome signaling. Overexpression of SHB1 enhanced the expression of PHYTOCHROME-INTERACTING FACTOR4 (PIF4) under red light and promoted proteasome-mediated degradation of phytochrome A and hypocotyl elongation under far-red light. A knockout allele suppressed LONG HYPOCOTYL IN FAR-RED LIGHT1 (HFR1) expression and showed several deetiolation phenotypes. Acts upstream of HFR1. Regulates seed development.
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Genomic context

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See SHB1 in Genome Data Viewer

Location:: chromosome: 4

Exon count:: 11

Sequence:: Chromosome: 4; NC_003075.7 (12962965..12966629, complement)

Chromosome 4 - NC_003075.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

results suggest that ABA negatively regulates SHB1 expression, at least in part, through the action of its downstream signaling component ABI5
Title: Abscisic acid regulates early seed development in Arabidopsis by ABI5-mediated transcription of SHORT HYPOCOTYL UNDER BLUE1.
The recruitment of SHB1 by MINI3 to its own and IKU2 promoters represents a novel two-step amplification to counter the low expression level of IKU2, which is a trigger for endosperm proliferation and seed cavity enlargement
Title: A WRKY transcription factor recruits the SYG1-like protein SHB1 to activate gene expression and seed cavity enlargement.
SHB1 associates with a protein complex through both Its SPX and EXS domains.
Title: SHORT HYPOCOTYL UNDER BLUE1 truncations and mutations alter its association with a signaling protein complex in Arabidopsis.
SHB1 represents signaling steps that regulate CO expression in leaves, contributing to a threshold expression of SOC1 in shoot apical meristem for floral initiation.
Title: SHB1 plays dual roles in photoperiodic and autonomous flowering.
SHB1 is a positive regulator of seed development that affects both cell size and cell number, and associates with MINISEED3 and HAIKU2 promoters.
Title: SHORT HYPOCOTYL UNDER BLUE1 associates with MINISEED3 and HAIKU2 promoters in vivo to regulate Arabidopsis seed development.
SHORT HYPOCOTYL UNDER BLUE1 associates with MINISEED3 and HAIKU2 promoters in vivo to regulate Arabidopsis seed development. [SHB1]
Title: SHORT HYPOCOTYL UNDER BLUE1 associates with MINISEED3 and HAIKU2 promoters in vivo to regulate Arabidopsis seed development.
SHB1 encodes a nuclear and cytosolic protein that has motifs homologous with SYG1 protein family members and is involved in regulating cryptochrome and possibly phytochrome-mediated light responses. [SHORT HYPOCOTYL UNDER BLUE1] [SHB1]
Title: Arabidopsis SHORT HYPOCOTYL UNDER BLUE1 contains SPX and EXS domains and acts in cryptochrome signaling.

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General gene information

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NM_118667.3

Supported by ESTs:

Gene Ontology Provided by TAIR

Process	Evidence Code	Pubs
acts_upstream_of_or_within endosperm development	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within positive regulation of cell size	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within red or far-red light signaling pathway	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within regulation of gene expression	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within regulation of seed development	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within regulation of seed growth	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in cytosol	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in plasma membrane	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: EXS (ERD1/XPR1/SYG1) family protein

NP_194265.2

SHORT HYPOCOTYL UNDER BLUE1 (SHB1); CONTAINS InterPro DOMAIN/s: EXS, C-terminal (InterPro:IPR004342), SPX, N-terminal (InterPro:IPR004331); BEST Arabidopsis thaliana protein match is: EXS (ERD1/XPR1/SYG1) family protein (TAIR:AT1G35350.1); Has 1169 Blast hits to 1111 proteins in 205 species: Archae - 2; Bacteria - 6; Metazoa - 265; Fungi - 425; Plants - 309; Viruses - 0; Other Eukaryotes - 162 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003075.7 Reference assembly

Range

12962965..12966629 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_118667.3 → NP_194265.2 EXS (ERD1/XPR1/SYG1) family protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_194265.2

Status: REVIEWED

UniProtKB/Swiss-Prot

Q6R8G6, Q9STK3

UniProtKB/TrEMBL

A0A654FSQ4

Conserved Domains (3) summary

cd14476
Location:2 → 286

SPX_PHO1_like; SPX domain of the plant protein PHOSPHATE1 (PHO1)

pfam03105
Location:3 → 291

SPX; SPX domain

pfam03124
Location:382 → 718

EXS; EXS family