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    CKX4 cytokinin oxidase 4 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 829096, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CKX4
    Official Full Name
    cytokinin oxidase 4
    Primary source
    TAIR:AT4G29740
    Locus tag
    AT4G29740
    See related
    Araport:AT4G29740
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATCKX4; cytokinin oxidase 4; T16L4.250; T16L4_250
    Summary
    It encodes a protein whose sequence is similar to cytokinin oxidase/dehydrogenase, which catalyzes the degradation of cytokinins.
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    Genomic context

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    See CKX4 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    5
    Sequence:
    Chromosome: 4; NC_003075.7 (14566183..14569380)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene nucleosome/chromatin assembly factor group C5 Neighboring gene uncharacterized protein Neighboring gene CRS1 / YhbY (CRM) domain-containing protein Neighboring gene ncRNA Neighboring gene target of trans acting-siR480/255 protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular and biochemical characterization of a cytokinin oxidase from maize. Bilyeu KD, et al. Plant Physiol, 2001 Jan. PMID 11154345, Free PMC Article
    2. Cytokinin-deficient transgenic Arabidopsis plants show multiple developmental alterations indicating opposite functions of cytokinins in the regulation of shoot and root meristem activity. Werner T, et al. Plant Cell, 2003 Nov. PMID 14555694, Free PMC Article
    3. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    NM_001341977.1
    NM_119120.2
    NM_179139.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables FAD binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables cytokinin dehydrogenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables cytokinin dehydrogenase activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables primary methylamine oxidase activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cytokinin catabolic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in cytokinin metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    cytokinin oxidase 4
    NP_194703.1
    • cytokinin oxidase 4 (CKX4); FUNCTIONS IN: primary amine oxidase activity, cytokinin dehydrogenase activity; INVOLVED IN: cytokinin catabolic process; LOCATED IN: endomembrane system; EXPRESSED IN: 15 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: Cytokinin dehydrogenase 1, FAD/cytokinin binding domain (InterPro:IPR015345), FAD-binding, type 2 (InterPro:IPR016166), FAD-linked oxidase-like, C-terminal (InterPro:IPR016164), FAD linked oxidase, N-terminal (InterPro:IPR006094); BEST Arabidopsis thaliana protein match is: cytokinin oxidase 2 (TAIR:AT2G19500.1); Has 4206 Blast hits to 4200 proteins in 818 species: Archae - 66; Bacteria - 2585; Metazoa - 17; Fungi - 1008; Plants - 323; Viruses - 0; Other Eukaryotes - 207 (source: NCBI BLink).
    NP_849470.1
    • cytokinin oxidase 4 (CKX4); FUNCTIONS IN: primary amine oxidase activity, cytokinin dehydrogenase activity; INVOLVED IN: cytokinin catabolic process; LOCATED IN: endomembrane system; EXPRESSED IN: 15 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: Cytokinin dehydrogenase 1, FAD/cytokinin binding domain (InterPro:IPR015345), FAD-binding, type 2 (InterPro:IPR016166), FAD-linked oxidase-like, C-terminal (InterPro:IPR016164), FAD linked oxidase, N-terminal (InterPro:IPR006094); BEST Arabidopsis thaliana protein match is: cytokinin oxidase 2 (TAIR:AT2G19500.1); Has 4201 Blast hits to 4198 proteins in 819 species: Archae - 66; Bacteria - 2589; Metazoa - 17; Fungi - 1008; Plants - 315; Viruses - 0; Other Eukaryotes - 206 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      14566183..14569380
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_119120.2 → NP_194703.1  cytokinin oxidase 4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_194703.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FUJ2, Q9SU77
      UniProtKB/TrEMBL
      A0A178UYT5, A0A5S9XX24
      Conserved Domains (1) summary
      PLN02441
      Location:3 → 524
      PLN02441; cytokinin dehydrogenase

    2. NM_001341977.1 → NP_001328306.1  cytokinin oxidase 4 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B473

    3. NM_179139.1 → NP_849470.1  cytokinin oxidase 4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_849470.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UYT5, A0A5S9XX24, F4JNR1
      Conserved Domains (2) summary
      pfam01565
      Location:64 → 218
      FAD_binding_4; FAD binding domain
      pfam09265
      Location:250 → 428
      Cytokin-bind; Cytokinin dehydrogenase 1, FAD and cytokinin binding
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FUJ2.2

    Gene LinkOut

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