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    BAM2 Leucine-rich receptor-like protein kinase family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 824129, updated on 18-Sep-2024

    Summary

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    Official Symbol
    BAM2
    Official Full Name
    Leucine-rich receptor-like protein kinase family protein
    Primary source
    TAIR:AT3G49670
    Locus tag
    AT3G49670
    See related
    Araport:AT3G49670
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    BARELY ANY MERISTEM 2
    Summary
    Encodes a CLAVATA1-related receptor kinase-like protein required for both shoot and flower meristem function. Very similar to BAM1,with more than 85% a.a. identity. It has a broad expression pattern and is involved in vascular strand development in the leaf, control of leaf shape, size and symmetry, male gametophyte development and ovule specification and function. Anthers of double mutants (bam1bam2) appeared abnormal at a very early stage and lack the endothecium, middle, and tapetum layers. Further analyses revealed that cells interior to the epidermis (in anther tissue) acquire some characteristics of pollen mother cells (PMCs), suggesting defects in cell fate specification. The pollen mother-like cells degenerate before the completion of meiosis, suggesting that these cells are defective. In addition, the BAM2 expression pattern supports both an early role in promoting somatic cell fates and a subsequent function in the PMCs.
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    Genomic context

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    See BAM2 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    2
    Sequence:
    Chromosome: 3; NC_003074.8 (18417568..18421263)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene FAD-binding protein Neighboring gene P-loop containing nucleoside triphosphate hydrolases superfamily protein Neighboring gene Transducin/WD40 repeat-like superfamily protein Neighboring gene ncRNA Neighboring gene branched-chain aminotransferase 3 Neighboring gene myb domain protein 84

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Solution structure and assembly of β-amylase 2 from Arabidopsis thaliana. Chandrasekharan NP, et al. Acta Crystallogr D Struct Biol, 2020 Apr 1. PMID 32254060, Free PMC Article
    2. Arabidopsis β-Amylase2 Is a K(+)-Requiring, Catalytic Tetramer with Sigmoidal Kinetics. Monroe JD, et al. Plant Physiol, 2017 Dec. PMID 29066669, Free PMC Article
    3. BAM receptors regulate stem cell specification and organ development through complex interactions with CLAVATA signaling. Deyoung BJ, et al. Genetics, 2008 Oct. PMID 18780746, Free PMC Article
    4. The BAM1/BAM2 receptor-like kinases are important regulators of Arabidopsis early anther development. Hord CL, et al. Plant Cell, 2006 Jul. PMID 16751349, Free PMC Article
    5. BAM1/2 receptor kinase signaling drives CLE peptide-mediated formative cell divisions in Arabidopsis roots. Crook AD, et al. Proc Natl Acad Sci U S A, 2020 Dec 22. PMID 33288706, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. BAM1/2 receptor kinase signaling drives CLE peptide-mediated formative cell divisions in Arabidopsis roots.
      Title: BAM1/2 receptor kinase signaling drives CLE peptide-mediated formative cell divisions in Arabidopsis roots.
    2. study of structure and assembly of the BAM2 tetramer
      Title: Solution structure and assembly of β-amylase 2 from Arabidopsis thaliana.
    3. Expression analysis indicated that BAM2 is more closely coexpressed with other starch degradation enzymes than any other BAM, suggesting that BAM2 may play an important role in starch degradation in plants.
      Title: Arabidopsis β-Amylase2 Is a K(+)-Requiring, Catalytic Tetramer with Sigmoidal Kinetics.
    4. CLV2, CLV1 and the CLV1 homologs BAM1 and BAM2 all bind to the CLV3-derived CLE peptide with similar kinetics.
      Title: CLAVATA2 forms a distinct CLE-binding receptor complex regulating Arabidopsis stem cell specification.
    5. BAM2 regulate stem cell specification and organ development through complex interactions with CLAVATA signaling
      Title: BAM receptors regulate stem cell specification and organ development through complex interactions with CLAVATA signaling.
    6. Analysis of BAM1 and BAM2 reveal a cell-cell communication process important for early anther development, including aspects of cell division and differentiation. [BAM2]
      Title: The BAM1/BAM2 receptor-like kinases are important regulators of Arabidopsis early anther development.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_114827.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables receptor serine/threonine kinase binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within anther development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within floral organ development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within gametophyte development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within microsporocyte differentiation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of meristem growth IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of meristem structural organization IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Leucine-rich receptor-like protein kinase family protein
    NP_190536.1
    • BARELY ANY MERISTEM 2 (BAM2); FUNCTIONS IN: protein serine/threonine kinase activity, protein kinase activity, ATP binding; INVOLVED IN: in 9 processes; LOCATED IN: plasma membrane; EXPRESSED IN: 29 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, catalytic domain (InterPro:IPR000719), Leucine-rich repeat-containing N-terminal domain, type 2 (InterPro:IPR013210), Leucine-rich repeat (InterPro:IPR001611), Serine-threonine/tyrosine-protein kinase (InterPro:IPR001245), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: Leucine-rich receptor-like protein kinase family protein (TAIR:AT5G65700.2); Has 214102 Blast hits to 137812 proteins in 4967 species: Archae - 148; Bacteria - 22093; Metazoa - 65883; Fungi - 10747; Plants - 88678; Viruses - 437; Other Eukaryotes - 26116 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      18417568..18421263
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_114827.4 → NP_190536.1  Leucine-rich receptor-like protein kinase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_190536.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WLN9, Q9M2Z1
      UniProtKB/TrEMBL
      A0A178VJB0, A0A5S9XJG4, A0A654FEG7
      Conserved Domains (2) summary
      PLN00113
      Location:27 → 961
      PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
      sd00033
      Location:71 → 94
      LRR_RI; leucine-rich repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9M2Z1.1

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