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    SRPK4 ser/arg-rich protein kinase 4 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 824469, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SRPK4
    Official Full Name
    ser/arg-rich protein kinase 4
    Primary source
    TAIR:AT3G53030
    Locus tag
    AT3G53030
    See related
    Araport:AT3G53030
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ser/arg-rich protein kinase 4
    Summary
    Encodes a protein kinase SRPK4 that specifically targets Arabidopsis Ser/Arg-rich (SR) slicing factors involved in RNA metabolism. In vitro kinase assay showed that SRPK4 phosphorylates the SR protein RSp31.
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    Genomic context

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    See SRPK4 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    4
    Sequence:
    Chromosome: 3; NC_003074.8 (19662195..19664553)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Ribosomal protein L24e family protein Neighboring gene late embryogenesis abundant protein, putative / LEA protein Neighboring gene D-galactoside/L-rhamnose binding SUEL lectin protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis. de la Fuente van Bentem S, et al. J Proteome Res, 2008 Jun. PMID 18433157
    2. Phosphoproteomics reveals extensive in vivo phosphorylation of Arabidopsis proteins involved in RNA metabolism. de la Fuente van Bentem S, et al. Nucleic Acids Res, 2006. PMID 16807317, Free PMC Article
    3. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_115163.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within protein phosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    ser/arg-rich protein kinase 4
    NP_566977.1
    • ser/arg-rich protein kinase 4 (SRPK4); FUNCTIONS IN: protein kinase activity, kinase activity; INVOLVED IN: response to oxidative stress, protein amino acid phosphorylation; LOCATED IN: cellular_component unknown; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase-like domain (InterPro:IPR011009), Protein kinase, catalytic domain (InterPro:IPR000719), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635); BEST Arabidopsis thaliana protein match is: Protein kinase superfamily protein (TAIR:AT3G44850.1); Has 38460 Blast hits to 29477 proteins in 1034 species: Archae - 2; Bacteria - 1392; Metazoa - 15648; Fungi - 7270; Plants - 6510; Viruses - 16; Other Eukaryotes - 7622 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      19662195..19664553
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_115163.5 → NP_566977.1  ser/arg-rich protein kinase 4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566977.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9XKK9, A0A654FFF7, F4J982, Q94AX8, Q9FYB3
      Conserved Domains (2) summary
      smart00220
      Location:42 → 466
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14136
      Location:31 → 466
      STKc_SRPK; Catalytic domain of the Serine/Threonine Kinase, Serine-aRginine Protein Kinase
    Nucleotide Protein
    Heading Accession and Version

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