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    ASF1B anti- silencing function 1b [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 833791, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ASF1B
    Official Full Name
    anti- silencing function 1b
    Primary source
    TAIR:AT5G38110
    Locus tag
    AT5G38110
    See related
    Araport:AT5G38110
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    anti- silencing function 1b; F16F17.110; F16F17_110; SGA01; SGA1
    Summary
    This gene is predicted to encode a silencing group A protein. Plant lines expressing RNAi constructs directed against SGA1 have reduced levels of agrobacterium-mediated root transformation. Its expression is regulated during cell cycle progression through E2F transcription factors.
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    Genomic context

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    See ASF1B in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    3
    Sequence:
    Chromosome: 5; NC_003076.8 (15208358..15210335)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene S-adenosyl-L-methionine-dependent methyltransferases superfamily protein Neighboring gene ncRNA Neighboring gene AMP-dependent synthetase and ligase family protein Neighboring gene HXXXD-type acyl-transferase family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Histone chaperone ASF1 is involved in gene transcription activation in response to heat stress in Arabidopsis thaliana. Weng M, et al. Plant Cell Environ, 2014 Sep. PMID 24548003
    2. ANTI-SILENCING FUNCTION1 proteins are involved in ultraviolet-induced DNA damage repair and are cell cycle regulated by E2F transcription factors in Arabidopsis. Lario LD, et al. Plant Physiol, 2013 Jun. PMID 23596192, Free PMC Article
    3. Arabidopsis homologues of the histone chaperone ASF1 are crucial for chromatin replication and cell proliferation in plant development. Zhu Y, et al. Plant J, 2011 May. PMID 21251110
    4. TOUSLED kinase activity oscillates during the cell cycle and interacts with chromatin regulators. Ehsan H, et al. Plant Physiol, 2004 Apr. PMID 15047893, Free PMC Article
    5. RNAi-mediated gene silencing reveals involvement of Arabidopsis chromatin-related genes in Agrobacterium-mediated root transformation. Crane YM, et al. Proc Natl Acad Sci U S A, 2007 Sep 18. PMID 17827277, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. This study unravels an important function of AtASF1A/B in plant heat stress response.
      Title: Histone chaperone ASF1 is involved in gene transcription activation in response to heat stress in Arabidopsis thaliana.
    2. ASF1A and ASF1B are regulated by cell cycle progression and are involved in DNA repair after UV-B irradiation.
      Title: ANTI-SILENCING FUNCTION1 proteins are involved in ultraviolet-induced DNA damage repair and are cell cycle regulated by E2F transcription factors in Arabidopsis.
    3. AtASF1A and AtASF1B proteins bind the histone H3. Simultaneous knockdown impairs chromatin replication and perturbs genome stability and function, causing S-phase and DNA repair checkpoint activation, and abnormal plant growth and development.
      Title: Arabidopsis homologues of the histone chaperone ASF1 are crucial for chromatin replication and cell proliferation in plant development.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_123171.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA-mediated transformation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within cell division IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within double-strand break repair via homologous recombination IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within mitotic cell size control checkpoint signaling IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of cell size IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within trichome branching IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    anti- silencing function 1b
    NP_198627.1
    • anti- silencing function 1b (ASF1B); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: DNA mediated transformation, nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; LOCATED IN: nucleus; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: Histone chaperone, ASF1-like (InterPro:IPR006818); BEST Arabidopsis thaliana protein match is: ASF1 like histone chaperone (TAIR:AT1G66740.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      15208358..15210335
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_123171.4 → NP_198627.1  anti- silencing function 1b [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_198627.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LS09
      UniProtKB/TrEMBL
      A0A178UQ02, A0A5S9Y9C1, A0A654G5W7
      Conserved Domains (1) summary
      pfam04729
      Location:1 → 154
      ASF1_hist_chap; ASF1 like histone chaperone
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LS09.1

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