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    RD21B Granulin repeat cysteine protease family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 834321, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RD21B
    Official Full Name
    Granulin repeat cysteine protease family protein
    Primary source
    TAIR:AT5G43060
    Locus tag
    AT5G43060
    See related
    Araport:AT5G43060
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    esponsive to dehydration 21B; MMG4.7; MMG4_7
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    Genomic context

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    See RD21B in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    5
    Sequence:
    Chromosome: 5; NC_003076.8 (17269310..17272298, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Cysteine/Histidine-rich C1 domain family protein Neighboring gene YCF20-like protein (DUF565) Neighboring gene pseudo Neighboring gene uncharacterized protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A Kunitz-type protease inhibitor regulates programmed cell death during flower development in Arabidopsis thaliana. Boex-Fontvieille E, et al. J Exp Bot, 2015 Oct. PMID 26160583
    2. PIRIN2 stabilizes cysteine protease XCP2 and increases susceptibility to the vascular pathogen Ralstonia solanacearum in Arabidopsis. Zhang B, et al. Plant J, 2014 Sep. PMID 24947605, Free PMC Article
    3. Arabidopsis protein disulfide isomerase-5 inhibits cysteine proteases during trafficking to vacuoles before programmed cell death of the endothelium in developing seeds. Andème Ondzighi C, et al. Plant Cell, 2008 Aug. PMID 18676877, Free PMC Article
    4. Isolation of intact vacuoles and proteomic analysis of tonoplast from suspension-cultured cells of Arabidopsis thaliana. Shimaoka T, et al. Plant Cell Physiol, 2004 Jun. PMID 15215502
    5. Proteome-wide screens for small ubiquitin-like modifier (SUMO) substrates identify Arabidopsis proteins implicated in diverse biological processes. Elrouby N, et al. Proc Natl Acad Sci U S A, 2010 Oct 5. PMID 20855607, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_123672.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables cysteine-type peptidase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum HDA PubMed 
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  
    located_in secretory vesicle HDA PubMed 
    located_in vacuole HDA PubMed 

    General protein information

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    Preferred Names
    Granulin repeat cysteine protease family protein
    NP_568620.1
    • Granulin repeat cysteine protease family protein; FUNCTIONS IN: cysteine-type peptidase activity, cysteine-type endopeptidase activity; INVOLVED IN: response to salt stress; LOCATED IN: vacuole; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase C1A, papain (InterPro:IPR013128), Proteinase inhibitor I29, cathepsin propeptide (InterPro:IPR013201), Granulin (InterPro:IPR000118), Peptidase C1A, papain C-terminal (InterPro:IPR000668), Peptidase, cysteine peptidase active site (InterPro:IPR000169); BEST Arabidopsis thaliana protein match is: Granulin repeat cysteine protease family protein (TAIR:AT1G47128.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      17269310..17272298 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_123672.4 → NP_568620.1  Granulin repeat cysteine protease family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568620.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WM94, Q9FMH8
      UniProtKB/TrEMBL
      A0A178US02, A0A5S9YB17
      Conserved Domains (3) summary
      smart00277
      Location:377 → 433
      GRAN; Granulin
      smart00848
      Location:50 → 109
      Inhibitor_I29; Cathepsin propeptide inhibitor domain (I29)
      pfam00112
      Location:138 → 353
      Peptidase_C1; Papain family cysteine protease
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FMH8.1

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