U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    MOL1 Leucine-rich repeat transmembrane protein kinase family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 835209, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    MOL1
    Official Full Name
    Leucine-rich repeat transmembrane protein kinase family protein
    Primary source
    TAIR:AT5G51350
    Locus tag
    AT5G51350
    See related
    Araport:AT5G51350
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    MFG13.5; MFG13_5; MORE LATERAL GROWTH1
    Summary
    Encodes a receptor-like kinase that represses secondary growth, the production of secondary vascular tissues.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See MOL1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    2
    Sequence:
    Chromosome: 5; NC_003076.8 (20867599..20870848, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene SWITCH1 Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein Neighboring gene Transcription elongation factor (TFIIS) family protein Neighboring gene RNI-like superfamily protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. MOL1 is required for cambium homeostasis in Arabidopsis. Gursanscky NR, et al. Plant J, 2016 May. PMID 26991973, Free PMC Article
    2. Characterization of transcriptome remodeling during cambium formation identifies MOL1 and RUL1 as opposing regulators of secondary growth. Agusti J, et al. PLoS Genet, 2011 Feb. PMID 21379334, Free PMC Article
    3. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help
    NM_124514.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within negative regulation of secondary growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Leucine-rich repeat transmembrane protein kinase family protein
    NP_199948.1
    • Leucine-rich repeat transmembrane protein kinase family protein; FUNCTIONS IN: protein serine/threonine kinase activity, kinase activity, ATP binding; INVOLVED IN: transmembrane receptor protein tyrosine kinase signaling pathway, protein amino acid phosphorylation; LOCATED IN: plasma membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, catalytic domain (InterPro:IPR000719), Leucine-rich repeat-containing N-terminal domain, type 2 (InterPro:IPR013210), Leucine-rich repeat (InterPro:IPR001611), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: Leucine-rich repeat protein kinase family protein (TAIR:AT5G61480.1); Has 108404 Blast hits to 45100 proteins in 1144 species: Archae - 34; Bacteria - 5225; Metazoa - 23563; Fungi - 1032; Plants - 70560; Viruses - 18; Other Eukaryotes - 7972 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      20867599..20870848 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_124514.3 → NP_199948.1  Leucine-rich repeat transmembrane protein kinase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_199948.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9YDP3, A0A654GAF8, A0A7G2FHD1, Q9FGN6
      Conserved Domains (5) summary
      PLN00113
      Location:2 → 890
      PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
      cd00116
      Location:337 → 549
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:103 → 127
      LRR_RI; leucine-rich repeat [structural motif]
      pfam08263
      Location:25 → 72
      LRRNT_2; Leucine rich repeat N-terminal domain
      cl21453
      Location:652 → 889
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools