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    Disease resistance protein (TIR-NBS-LRR class) family [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 835237, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Disease resistance protein (TIR-NBS-LRR class) family
    Primary source
    TAIR:AT5G51630
    Locus tag
    AT5G51630
    See related
    Araport:AT5G51630
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    K17N15.18; K17N15_18
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    Genomic context

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    Location:
    chromosome: 5
    Exon count:
    7
    Sequence:
    Chromosome: 5; NC_003076.8 (20969128..20975940)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Ribosomal protein L11 family protein Neighboring gene Uncharacterized protein family (UPF0172) Neighboring gene trichome birefringence-like protein (DUF828) Neighboring gene uncharacterized protein Neighboring gene cleavage and polyadenylation specificity factor 160

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_001203587.1
    NM_001344947.1
    NM_001344948.1
    NM_124542.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ADP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in defense response IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Disease resistance protein (TIR-NBS-LRR class) family
    NP_001190516.1
    • Disease resistance protein (TIR-NBS-LRR class) family; FUNCTIONS IN: transmembrane receptor activity, ATP binding; INVOLVED IN: signal transduction, apoptosis, defense response, innate immune response; LOCATED IN: intrinsic to membrane; EXPRESSED IN: 9 plant structures; EXPRESSED DURING: 4 anthesis, petal differentiation and expansion stage, E expanded cotyledon stage, D bilateral stage; CONTAINS InterPro DOMAIN/s: NB-ARC (InterPro:IPR002182), Leucine-rich repeat (InterPro:IPR001611), Disease resistance protein (InterPro:IPR000767), Toll-Interleukin receptor (InterPro:IPR000157); BEST Arabidopsis thaliana protein match is: disease resistance protein (TIR-NBS-LRR class), putative (TAIR:AT4G16890.1).
    NP_199976.2
    • Disease resistance protein (TIR-NBS-LRR class) family; FUNCTIONS IN: transmembrane receptor activity, nucleoside-triphosphatase activity, nucleotide binding, ATP binding; INVOLVED IN: signal transduction, defense response, apoptosis, innate immune response; LOCATED IN: intrinsic to membrane, endomembrane system; EXPRESSED IN: 9 plant structures; EXPRESSED DURING: 4 anthesis, petal differentiation and expansion stage, E expanded cotyledon stage, D bilateral stage; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), NB-ARC (InterPro:IPR002182), Leucine-rich repeat (InterPro:IPR001611), Toll-Interleukin receptor (InterPro:IPR000157), Disease resistance protein (InterPro:IPR000767); BEST Arabidopsis thaliana protein match is: disease resistance protein (TIR-NBS-LRR class), putative (TAIR:AT4G16890.1); Has 26204 Blast hits to 17984 proteins in 706 species: Archae - 26; Bacteria - 1932; Metazoa - 2433; Fungi - 202; Plants - 20704; Viruses - 0; Other Eukaryotes - 907 (source: NCBI BLink).
    NP_851172.1
    • Disease resistance protein (TIR-NBS-LRR class) family; FUNCTIONS IN: transmembrane receptor activity, nucleoside-triphosphatase activity, nucleotide binding, ATP binding; INVOLVED IN: signal transduction, apoptosis, defense response, innate immune response; LOCATED IN: intrinsic to membrane; EXPRESSED IN: 9 plant structures; EXPRESSED DURING: 4 anthesis, petal differentiation and expansion stage, E expanded cotyledon stage, D bilateral stage; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), NB-ARC (InterPro:IPR002182), Leucine-rich repeat (InterPro:IPR001611), Toll-Interleukin receptor (InterPro:IPR000157), Disease resistance protein (InterPro:IPR000767); BEST Arabidopsis thaliana protein match is: disease resistance protein (TIR-NBS-LRR class), putative (TAIR:AT4G16890.1); Has 26294 Blast hits to 18044 proteins in 708 species: Archae - 26; Bacteria - 1938; Metazoa - 2435; Fungi - 200; Plants - 20794; Viruses - 0; Other Eukaryotes - 901 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      20969128..20975940
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001344946.1 → NP_001330479.1  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BAZ5, Q9FHM1

    2. NM_180841.3 → NP_851172.1  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_851172.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0WPW2, Q9FHM1
      Conserved Domains (6) summary
      cd09293
      Location:807 → 868
      AMN1; Antagonist of mitotic exit network protein 1
      PLN03210
      Location:2 → 1167
      PLN03210; Resistant to P. syringae 6; Provisional
      sd00033
      Location:649 → 672
      LRR_RI; leucine-rich repeat [structural motif]
      pfam01582
      Location:11 → 173
      TIR; TIR domain
      pfam07725
      Location:762 → 781
      LRR_3; Leucine Rich Repeat
      pfam13207
      Location:209 → 294
      AAA_17; AAA domain

    3. NM_124542.3 → NP_199976.2  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_199976.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4KDB9, Q9FHM1
      Conserved Domains (6) summary
      cd09293
      Location:743 → 804
      AMN1; Antagonist of mitotic exit network protein 1
      PLN03210
      Location:2 → 1103
      PLN03210; Resistant to P. syringae 6; Provisional
      sd00033
      Location:585 → 608
      LRR_RI; leucine-rich repeat [structural motif]
      pfam01582
      Location:1 → 109
      TIR; TIR domain
      pfam07725
      Location:698 → 717
      LRR_3; Leucine Rich Repeat
      pfam13207
      Location:145 → 230
      AAA_17; AAA domain

    4. NM_001344947.1 → NP_001330480.1  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BAX9

    5. NM_001344948.1 → NP_001330481.1  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BAZ5, Q9FHM1

    6. NM_001203587.1 → NP_001190516.1  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001190516.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4KDB8, Q9FHM1
      Conserved Domains (5) summary
      cd09293
      Location:759 → 820
      AMN1; Antagonist of mitotic exit network protein 1
      PLN03210
      Location:2 → 1119
      PLN03210; Resistant to P. syringae 6; Provisional
      sd00033
      Location:601 → 624
      LRR_RI; leucine-rich repeat [structural motif]
      pfam01582
      Location:11 → 173
      TIR; TIR domain
      pfam07725
      Location:714 → 733
      LRR_3; Leucine Rich Repeat
    Nucleotide Protein
    Heading Accession and Version

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