ARM repeat superfamily protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Full Name: ARM repeat superfamily protein
Primary source: TAIR:AT5G53480
Locus tag: AT5G53480
See related: Araport:AT5G53480
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: AtKPNB1; homolog of human KPNB1; KPNB1; MNC6.1; MNC6_1
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Genomic context

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See in Genome Data Viewer

Location:: chromosome: 5

Exon count:: 3

Sequence:: Chromosome: 5; NC_003076.8 (21713245..21717878)

Chromosome 5 - NC_003076.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

AtKPNB1, an Arabidopsis importin-beta protein, is downstream of the RING E3 ubiquitin ligase AtAIRP1 in the ABA-mediated drought stress response.
Title: AtKPNB1, an Arabidopsis importin-β protein, is downstream of the RING E3 ubiquitin ligase AtAIRP1 in the ABA-mediated drought stress response.
At5g53480 is required for abscisic acid response and drought tolerance.
Title: An Arabidopsis homolog of importin β1 is required for ABA response and drought tolerance.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_124727.3

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables nucleocytoplasmic carrier activity	IDA Inferred from Direct Assay more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables small GTPase binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within protein import into nucleus	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within protein transport	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
located_in cytoplasm	ISM Inferred from Sequence Model more info
NOT located_in cytosol	RCA inferred from Reviewed Computational Analysis more info	PubMed
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: ARM repeat superfamily protein

NP_200160.1

ARM repeat superfamily protein; FUNCTIONS IN: protein transporter activity, binding; INVOLVED IN: intracellular protein transport, protein import into nucleus, docking; LOCATED IN: nucleus, chloroplast, nuclear pore, cytoplasm; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Importin-beta, N-terminal (InterPro:IPR001494), Armadillo-like helical (InterPro:IPR011989), Armadillo-type fold (InterPro:IPR016024); BEST Arabidopsis thaliana protein match is: ARM repeat superfamily protein (TAIR:AT3G08947.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003076.8 Reference assembly

Range

21713245..21717878

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_124727.3 → NP_200160.1 ARM repeat superfamily protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_200160.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q8GZ46, Q9FJD4

UniProtKB/TrEMBL

A0A178UKY5, A0A5S9YEC2

Conserved Domains (2) summary

COG5215
Location:2 → 870

KAP95; Karyopherin (importin) beta [Intracellular trafficking and secretion]

sd00044
Location:368 → 396

HEAT; HEAT repeat [structural motif]