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    MPS1 multipolar spindle 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 835898, updated on 18-Sep-2024

    Summary

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    Official Symbol
    MPS1
    Official Full Name
    multipolar spindle 1
    Primary source
    TAIR:AT5G57880
    Locus tag
    AT5G57880
    See related
    Araport:AT5G57880
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA PUTATIVE RECOMBINATION INITIATION DEFECTS 2; ATPRD2; MULTIPOLAR SPINDLE 1; PRD2; PUTATIVE RECOMBINATION INITIATION DEFECTS 2
    Summary
    Encodes MULTIPOLAR SPINDLE 1 (MPS1), involved in meiotic spindle organization.
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    Genomic context

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    See MPS1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    11
    Sequence:
    Chromosome: 5; NC_003076.8 (23443962..23447244)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Ubiquitin-like superfamily protein Neighboring gene MIF4G domain-containing protein / MA3 domain-containing protein Neighboring gene ncRNA Neighboring gene tRNA-Met Neighboring gene uncharacterized protein Neighboring gene Glutamine amidotransferase type 1 family protein Neighboring gene ncRNA Neighboring gene SKP1 interacting partner 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structural and functional characterization of the protein kinase Mps1 in Arabidopsis thaliana. de Oliveira EA, et al. PLoS One, 2012. PMID 23049844, Free PMC Article
    2. MULTIPOLAR SPINDLE 1 (MPS1), a novel coiled-coil protein of Arabidopsis thaliana, is required for meiotic spindle organization. Jiang H, et al. Plant J, 2009 Sep. PMID 19500302
    3. A high throughput genetic screen identifies new early meiotic recombination functions in Arabidopsis thaliana. De Muyt A, et al. PLoS Genet, 2009 Sep. PMID 19763177, Free PMC Article
    4. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Mps1 might be a universal component of the Spindle Assembly Checkpoint machinery across very distant lineages of eukaryotes
      Title: Structural and functional characterization of the protein kinase Mps1 in Arabidopsis thaliana.
    2. MPS1 encodes a putative coiled-coil protein that plays an important role in meiotic spindle organization. [MPS1]
      Title: MULTIPOLAR SPINDLE 1 (MPS1), a novel coiled-coil protein of Arabidopsis thaliana, is required for meiotic spindle organization.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    NM_001345277.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within chiasma assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within chromosome segregation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within embryo sac development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within male meiotic nuclear division IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within meiotic DNA double-strand break formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within meiotic spindle organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within plant-type sporogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within pollen development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    multipolar spindle 1
    NP_001318822.1
    • MULTIPOLAR SPINDLE 1 (MPS1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      23443962..23447244
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001345277.1 → NP_001318822.1  multipolar spindle 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      C9X3W2, F4KDF5, Q9FJM6
      UniProtKB/TrEMBL
      A0A5S9YF85, A0A654GC44
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    F4KDF5.2

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