ERS glutamate tRNA synthetase [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: ERS
Official Full Name: glutamate tRNA synthetase
Primary source: TAIR:AT5G64050
Locus tag: AT5G64050
See related: Araport:AT5G64050
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ATERS; ETHYLENE RESPONSE SENSOR; glutamate tRNA synthetase; OVA3; OVULE ABORTION 3
Summary: Glutamate-tRNA ligase. Targeted to mitochondria and chloroplast. Its inactivation causes developmental arrest of chloroplasts and mitochondria in Nicotiana benthamiana.
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Chromosome 5 - NC_003076.8 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

NM_125801.4

Function	Evidence Code	Pubs
enables glutamate-tRNA ligase activity	IEA Inferred from Electronic Annotation more info
enables glutamate-tRNA ligase activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables tRNA binding	IEA Inferred from Electronic Annotation more info
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within chloroplast organization	TAS Traceable Author Statement more info	PubMed
acts_upstream_of_or_within glutamyl-tRNA aminoacylation	ISS Inferred from Sequence or Structural Similarity more info	PubMed
acts_upstream_of_or_within mitochondrion organization	TAS Traceable Author Statement more info	PubMed
acts_upstream_of_or_within plant ovule development	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within tRNA aminoacylation	TAS Traceable Author Statement more info

Component	Evidence Code	Pubs
located_in chloroplast	HDA more info	PubMed
located_in chloroplast	IDA Inferred from Direct Assay more info	PubMed
located_in chloroplast stroma	HDA more info	PubMed
located_in cytoplasm	ISM Inferred from Sequence Model more info
located_in mitochondrion	IDA Inferred from Direct Assay more info	PubMed
located_in plastid	HDA more info	PubMed

NP_201210.1

glutamate tRNA synthetase (ERS); FUNCTIONS IN: protein binding, glutamate-tRNA ligase activity; INVOLVED IN: chloroplast organization, glutamyl-tRNA aminoacylation, mitochondrion organization, tRNA aminoacylation, ovule development; LOCATED IN: mitochondrion, chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Aminoacyl-tRNA synthetase, class I, conserved site (InterPro:IPR001412), Glutamyl/glutaminyl-tRNA synthetase, class Ic, alpha-bundle domain (InterPro:IPR020061), Glutamyl-tRNA synthetase, class Ic, bacterial/mitochondrial (InterPro:IPR004527), Glutamyl/glutaminyl-tRNA synthetase, class Ic, N-terminal (InterPro:IPR020060), Aminoacyl-tRNA synthetase, class I, anticodon-binding (InterPro:IPR008925), Glutamyl/glutaminyl-tRNA synthetase, class Ic, catalytic domain (InterPro:IPR020058), Rossmann-like alpha/beta/alpha sandwich fold (InterPro:IPR014729), Glutamyl/glutaminyl-tRNA synthetase, class Ic (InterPro:IPR000924), Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 (InterPro:IPR020751); BEST Arabidopsis thaliana protein match is: Glutamyl/glutaminyl-tRNA synthetase, class Ic (TAIR:AT5G26710.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).