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    GMD1 GDP-D-mannose 4,6-dehydratase 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 836760, updated on 18-Sep-2024

    Summary

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    Official Symbol
    GMD1
    Official Full Name
    GDP-D-mannose 4,6-dehydratase 1
    Primary source
    TAIR:AT5G66280
    Locus tag
    AT5G66280
    See related
    Araport:AT5G66280
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ''GDP-D-mannose 4; 6-dehydratase 1; 6-DEHYDRATASE 1; 6-dehydratase 1''; GDP-D-mannose 4; GDP-D-MANNOSE 4; K1L20.6; K1L20_6
    Summary
    GDP-D-mannose 4,6-dehydratase
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    Genomic context

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    See GMD1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    1
    Sequence:
    Chromosome: 5; NC_003076.8 (26476166..26477754)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene SAUR-like auxin-responsive protein family Neighboring gene Zinc finger C-x8-C-x5-C-x3-H type family protein Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene NAC domain containing protein 105 Neighboring gene ATP binding microtubule motor family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Proteomic profiling of tandem affinity purified 14-3-3 protein complexes in Arabidopsis thaliana. Chang IF, et al. Proteomics, 2009 Jun. PMID 19452453, Free PMC Article
    2. 14-3-3 proteins fine-tune plant nutrient metabolism. Shin R, et al. FEBS Lett, 2011 Jan 3. PMID 21094157
    3. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article
    4. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
    5. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    • At5g66280_Arabidopsis_lyrata_ssp._lyrata_CAN1 (e-PCR)
    • At5g66280_Arabidopsis_lyrata_ssp._petraea_GER1 (e-PCR)

    Homology

    NM_126026.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables GDP-mannose 4,6-dehydratase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in 'de novo' GDP-L-fucose biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in GDP-mannose metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi apparatus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plastid HDA PubMed 

    General protein information

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    Preferred Names
    GDP-D-mannose 4,6-dehydratase 1
    NP_201429.1
    • ''GDP-D-mannose 4,6-dehydratase 1'' (GMD1); FUNCTIONS IN: protein binding, GDP-mannose 4,6-dehydratase activity; INVOLVED IN: cellular metabolic process, GDP-mannose metabolic process, nucleotide-sugar metabolic process, metabolic process; LOCATED IN: intracellular; EXPRESSED IN: inflorescence meristem, root, flower; EXPRESSED DURING: 4 anthesis, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: NAD-dependent epimerase/dehydratase (InterPro:IPR001509), NAD(P)-binding domain (InterPro:IPR016040), GDP-mannose 4,6-dehydratase (InterPro:IPR006368); BEST Arabidopsis thaliana protein match is: NAD(P)-binding Rossmann-fold superfamily protein (TAIR:AT3G51160.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      26476166..26477754
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_126026.3 → NP_201429.1  GDP-D-mannose 4,6-dehydratase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_201429.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q058I8, Q9SNY3
      UniProtKB/TrEMBL
      A0A178U7H7, A0A5S9YHI3, A0A654GF27, A0A7G2FQD0
      Conserved Domains (1) summary
      PLN02653
      Location:11 → 351
      PLN02653; GDP-mannose 4,6-dehydratase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SNY3.1

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