U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    YUC6 Flavin-binding monooxygenase family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 832638, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    YUC6
    Official Full Name
    Flavin-binding monooxygenase family protein
    Primary source
    TAIR:AT5G25620
    Locus tag
    AT5G25620
    See related
    Araport:AT5G25620
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtYUC6; T14C9.160; T14C9_160; YUCCA6
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See YUC6 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    4
    Sequence:
    Chromosome: 5; NC_003076.8 (8934941..8938768, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene pseudo Neighboring gene tRNA-Phe Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein Neighboring gene Rhomboid-related intramembrane serine protease family protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Phytochrome-interacting factors orchestrate hypocotyl adventitious root initiation in Arabidopsis. Li QQ, et al. Development, 2022 May 15. PMID 35502748
    2. A novel thiol-reductase activity of Arabidopsis YUC6 confers drought tolerance independently of auxin biosynthesis. Cha JY, et al. Nat Commun, 2015 Aug 28. PMID 26314500, Free PMC Article
    3. Transgenic poplar expressing Arabidopsis YUCCA6 exhibits auxin-overproduction phenotypes and increased tolerance to abiotic stress. Ke Q, et al. Plant Physiol Biochem, 2015 Sep. PMID 25980973
    4. Roles of YUCCAs in auxin biosynthesis and drought stress responses in plants. Cheol Park H, et al. Plant Signal Behav, 2013 Jun. PMID 23603963, Free PMC Article
    5. The biochemical mechanism of auxin biosynthesis by an arabidopsis YUCCA flavin-containing monooxygenase. Dai X, et al. J Biol Chem, 2013 Jan 18. PMID 23188833, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Arabidopsis plants overexpressing YUC6 display enhanced IAA-related phenotypes and exhibit improved drought stress tolerance, low rate of water loss and controlled ROS accumulation under drought and oxidative stresses.
      Title: A novel thiol-reductase activity of Arabidopsis YUC6 confers drought tolerance independently of auxin biosynthesis.
    2. Transgenic poplar expressing Arabidopsis YUCCA6 exhibits auxin-overproduction phenotypes and increased tolerance to abiotic stress.
      Title: Transgenic poplar expressing Arabidopsis YUCCA6 exhibits auxin-overproduction phenotypes and increased tolerance to abiotic stress.
    3. YUCCA6 enhances drought tolerance through regulated reactive oxygen species homeostasis
      Title: Roles of YUCCAs in auxin biosynthesis and drought stress responses in plants.
    4. a functional YUCCA pathway of auxin biosynthesis in potato
      Title: Overexpression of Arabidopsis YUCCA6 in potato results in high-auxin developmental phenotypes and enhanced resistance to water deficit.
    5. YUC6 uses NADPH and oxygen to convert indole-3-pyruvic acid to indole-3-acetic acid.
      Title: The biochemical mechanism of auxin biosynthesis by an arabidopsis YUCCA flavin-containing monooxygenase.
    6. Arabidopsis plants over-expressing YUCCA6 displayed dramatic longevity. In addition, plants over-expressing YUCCA6 exhibited classical, delayed dark-induced and hormone-induced senescence in leaves.
      Title: YUCCA6 over-expression demonstrates auxin function in delaying leaf senescence in Arabidopsis thaliana.
    7. SPL regulates auxin homeostasis by repressing the transcription of YUC2 and YUC6 and participates in lateral organ morphogenesis.
      Title: SPOROCYTELESS modulates YUCCA expression to regulate the development of lateral organs in Arabidopsis.
    8. results identify YUCCA6 as a functional member of the YUCCA family with unique roles in growth and development
      Title: yucca6, a dominant mutation in Arabidopsis, affects auxin accumulation and auxin-related phenotypes.
    Submit: New GeneRIF Correction

    General gene information

    Go to the top of the page Help
    NM_001203470.1
    NM_122473.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables N,N-dimethylaniline monooxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables NADP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables flavin adenine dinucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables indole-3-pyruvate monooxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein-disulfide reductase (NAD(P)H) activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in auxin biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within auxin biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within drought recovery IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to ethylene IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to metal ion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within response to oxidative stress IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within somatic embryogenesis IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Flavin-binding monooxygenase family protein
    NP_001190399.2
    • YUCCA6 (YUC6); FUNCTIONS IN: NADP or NADPH binding, oxidoreductase activity, monooxygenase activity, FAD binding, flavin-containing monooxygenase activity; INVOLVED IN: auxin biosynthetic process; EXPRESSED IN: sepal; EXPRESSED DURING: petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Pyridine nucleotide-disulphide oxidoreductase, class-II (InterPro:IPR000103), FAD-dependent pyridine nucleotide-disulphide oxidoreductase (InterPro:IPR013027), Flavin-containing monooxygenase-like (InterPro:IPR020946); BEST Arabidopsis thaliana protein match is: Flavin-binding monooxygenase family protein (TAIR:AT4G13260.1).
    NP_197944.2
    • YUCCA6 (YUC6); FUNCTIONS IN: NADP or NADPH binding, oxidoreductase activity, monooxygenase activity, FAD binding, flavin-containing monooxygenase activity; INVOLVED IN: auxin biosynthetic process; EXPRESSED IN: sepal; EXPRESSED DURING: petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Pyridine nucleotide-disulphide oxidoreductase, class-II (InterPro:IPR000103), FAD-dependent pyridine nucleotide-disulphide oxidoreductase (InterPro:IPR013027), Flavin-containing monooxygenase-like (InterPro:IPR020946); BEST Arabidopsis thaliana protein match is: Flavin-binding monooxygenase family protein (TAIR:AT4G13260.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      8934941..8938768 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_122473.3 → NP_197944.2  Flavin-binding monooxygenase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_197944.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8VZ59
      UniProtKB/TrEMBL
      A0A178UES9, A0A5S9Y7R2
      Conserved Domains (1) summary
      COG2072
      Location:33 → 353
      CzcO; Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism]

    2. NM_001203470.1 → NP_001190399.2  Flavin-binding monooxygenase family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UES9, A0A5S9Y7R2, F4JY69
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8VZ59.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools