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    CYCH;1 cyclin H;1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 832824, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CYCH;1
    Official Full Name
    cyclin H;1
    Primary source
    TAIR:AT5G27620
    Locus tag
    AT5G27620
    See related
    Araport:AT5G27620
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    cyclin H;1; F15A18.80; F15A18_80
    Summary
    core cell cycle genes
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    Genomic context

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    See CYCH;1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    13
    Sequence:
    Chromosome: 5; NC_003076.8 (9771287..9774920)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene JAB1/Mov34/MPN/PAD-1 ubiquitin protease Neighboring gene protein ALWAYS EARLY 1 Neighboring gene acyl-CoA binding protein 5 Neighboring gene translation initiation factor 3B1 Neighboring gene Tudor/PWWP/MBT superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. CYCLIN H;1 regulates drought stress responses and blue light-induced stomatal opening by inhibiting reactive oxygen species accumulation in Arabidopsis. Zhou XF, et al. Plant Physiol, 2013 Jun. PMID 23656895, Free PMC Article
    2. Diverse phosphoregulatory mechanisms controlling cyclin-dependent kinase-activating kinases in Arabidopsis. Shimotohno A, et al. Plant J, 2006 Sep. PMID 16856985
    3. The plant-specific kinase CDKF;1 is involved in activating phosphorylation of cyclin-dependent kinase-activating kinases in Arabidopsis. Shimotohno A, et al. Plant Cell, 2004 Nov. PMID 15486101, Free PMC Article
    4. A tandem affinity purification-based technology platform to study the cell cycle interactome in Arabidopsis thaliana. Van Leene J, et al. Mol Cell Proteomics, 2007 Jul. PMID 17426018
    5. Functional modules in the Arabidopsis core cell cycle binary protein-protein interaction network. Boruc J, et al. Plant Cell, 2010 Apr. PMID 20407024, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. CYCLIN H;1 regulates drought stress responses and blue light-induced stomatal opening by inhibiting reactive oxygen species accumulation in Arabidopsis.
      Title: CYCLIN H;1 regulates drought stress responses and blue light-induced stomatal opening by inhibiting reactive oxygen species accumulation in Arabidopsis.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001344019.1
    NM_001344020.1
    NM_122644.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables cyclin-dependent protein serine/threonine kinase regulator activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within reactive oxygen species metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of DNA-templated transcription IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of response to water deprivation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of stomatal movement IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within response to blue light IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in response to blue light IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to water deprivation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in response to water deprivation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within stomatal opening IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    cyclin H;1
    NP_198114.2
    • cyclin H;1 (CYCH;1); CONTAINS InterPro DOMAIN/s: Cyclin H (InterPro:IPR015432), Cyclin-like (InterPro:IPR011028), Transcription regulator cyclin (InterPro:IPR015429), Cyclin-related (InterPro:IPR013763), Cyclin, N-terminal (InterPro:IPR006671), Cyclin (InterPro:IPR006670); BEST Arabidopsis thaliana protein match is: Cyclin family protein (TAIR:AT5G48640.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      9771287..9774920
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_122644.5 → NP_198114.2  cyclin H;1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_198114.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8W5S1
      UniProtKB/TrEMBL
      A0A5S9YA20
      Conserved Domains (3) summary
      TIGR00569
      Location:4 → 317
      ccl1; cyclin ccl1
      cd00043
      Location:79 → 165
      CYCLIN; Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB ...
      pfam16899
      Location:176 → 281
      Cyclin_C_2; Cyclin C-terminal domain

    2. NM_001344020.1 → NP_001330468.1  cyclin H;1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BAX1, A0A5S9YA20

    3. NM_001344019.1 → NP_001330469.1  cyclin H;1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BAW8, A0A5S9YA20
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8W5S1.1

    Gene LinkOut

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