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    GNA1 glucose-6-phosphate acetyltransferase 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 831433, updated on 18-Sep-2024

    Summary

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    Official Symbol
    GNA1
    Official Full Name
    glucose-6-phosphate acetyltransferase 1
    Primary source
    TAIR:AT5G15770
    Locus tag
    AT5G15770
    See related
    Araport:AT5G15770
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtGNA1; F14F8.150; F14F8_150; glucose-6-phosphate acetyltransferase 1
    Summary
    Encodes a putative glucose-6-phosphate acetyltransferase that is likely involved in UDP-N-acetylglucosamine biosynthesis. A GFP:GNA1 fusion protein localizes to the endoplasmic reticulum.
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    Genomic context

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    See GNA1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    1
    Sequence:
    Chromosome: 5; NC_003076.8 (5144091..5144580, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene O-fucosyltransferase family protein Neighboring gene uncharacterized protein Neighboring gene Alpha-L RNA-binding motif/Ribosomal protein S4 family protein Neighboring gene Ribosomal protein PSRP-3/Ycf65 Neighboring gene Pollen Ole e 1 allergen and extensin family protein Neighboring gene RING/U-box superfamily protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A missense mutation in the glucosamine-6-phosphate N-acetyltransferase-encoding gene causes temperature-dependent growth defects and ectopic lignin deposition in Arabidopsis. Nozaki M, et al. Plant Cell, 2012 Aug. PMID 22932674, Free PMC Article
    2. Crystal structure and functional characterization of a glucosamine-6-phosphate N-acetyltransferase from Arabidopsis thaliana. Riegler H, et al. Biochem J, 2012 Apr 15. PMID 22329777
    3. A novel short-root gene encodes a glucosamine-6-phosphate acetyltransferase required for maintaining normal root cell shape in rice. Jiang H, et al. Plant Physiol, 2005 May. PMID 15849305, Free PMC Article
    4. CrY2H-seq: a massively multiplexed assay for deep-coverage interactome mapping. Wanamaker SA, et al. Nat Methods, 2017 Aug. PMID 28650476, Free PMC Article
    5. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. A missense mutation in GNA1 encoding gene causes growth retardation and abnormal ectopic lignin deposition under high temperature conditions.
      Title: A missense mutation in the glucosamine-6-phosphate N-acetyltransferase-encoding gene causes temperature-dependent growth defects and ectopic lignin deposition in Arabidopsis.
    2. qPCR (quantitative PCR) revealed the ubiquitous expression of AtGNA in all organs of Arabidopsis plants
      Title: Crystal structure and functional characterization of a glucosamine-6-phosphate N-acetyltransferase from Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_121582.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables glucosamine 6-phosphate N-acetyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables glucosamine 6-phosphate N-acetyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within N-acetylglucosamine metabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in UDP-N-acetylglucosamine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi apparatus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    glucose-6-phosphate acetyltransferase 1
    NP_197081.1
    • glucose-6-phosphate acetyltransferase 1 (GNA1); FUNCTIONS IN: glucosamine 6-phosphate N-acetyltransferase activity, N-acetyltransferase activity; INVOLVED IN: metabolic process; LOCATED IN: cellular_component unknown; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: GCN5-related N-acetyltransferase, C-terminal (InterPro:IPR022610), GCN5-related N-acetyltransferase (InterPro:IPR000182), Acyl-CoA N-acyltransferase (InterPro:IPR016181); Has 806 Blast hits to 799 proteins in 307 species: Archae - 17; Bacteria - 208; Metazoa - 186; Fungi - 170; Plants - 47; Viruses - 3; Other Eukaryotes - 175 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      5144091..5144580 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_121582.2 → NP_197081.1  glucose-6-phosphate acetyltransferase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_197081.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LFU9
      UniProtKB/TrEMBL
      A0A178U7Q6, A0A5S9Y4G3, A0A654G1I6
      Conserved Domains (1) summary
      PLN02706
      Location:1 → 148
      PLN02706; glucosamine 6-phosphate N-acetyltransferase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LFU9.1

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