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    eIF6B Translation initiation factor IF6 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 818569, updated on 18-Sep-2024

    Summary

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    Official Symbol
    eIF6B
    Official Full Name
    Translation initiation factor IF6
    Primary source
    TAIR:AT2G39820
    Locus tag
    AT2G39820
    See related
    Araport:AT2G39820
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    eukaryotic initiation factor 6B; T5I7.12; T5I7_12
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    Genomic context

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    See eIF6B in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    6
    Sequence:
    Chromosome: 2; NC_003071.7 (16618226..16619750)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Integral membrane Yip1 family protein Neighboring gene ubiquitin-protein ligase Neighboring gene DA1-related protein 2 Neighboring gene type one serine/threonine protein phosphatase 4 Neighboring gene Subtilisin-like serine endopeptidase family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Involvement of Arabidopsis RACK1 in protein translation and its regulation by abscisic acid. Guo J, et al. Plant Physiol, 2011 Jan. PMID 21098678, Free PMC Article
    2. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article
    3. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_129541.3

    Gene Ontology Provided by TAIR

    Component Evidence Code Pubs
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Translation initiation factor IF6
    NP_181512.1
    • Translation initiation factor IF6; FUNCTIONS IN: ribosome binding, translation initiation factor activity; INVOLVED IN: translational initiation, mature ribosome assembly; LOCATED IN: cellular_component unknown; EXPRESSED IN: 7 plant structures; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage, 4 anthesis, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Translation initiation factor IF6 (InterPro:IPR002769); BEST Arabidopsis thaliana protein match is: Translation initiation factor IF6 (TAIR:AT3G55620.1); Has 945 Blast hits to 938 proteins in 349 species: Archae - 262; Bacteria - 0; Metazoa - 235; Fungi - 146; Plants - 134; Viruses - 0; Other Eukaryotes - 168 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      16618226..16619750
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_129541.3 → NP_181512.1  Translation initiation factor IF6 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_181512.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O22290
      UniProtKB/TrEMBL
      A0A178VNM1, A0A5S9X5I8
      Conserved Domains (1) summary
      cl00241
      Location:1 → 246
      IF6; Ribosome anti-association factor IF6 binds the large ribosomal subunit and prevents the two subunits from associating during translation initiation. IF6 comprises a family of translation factors that includes both eukaryotic (eIF6) and archeal (aIF6) ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O22290.1

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